SynthesisBMC musculoskeletal disorders2019
The association between occupational loading and spine degeneration on imaging - a systematic review and meta-analysis.
Synthesis in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Intervertebral Disc Disease of the Lumbar Spine in Health Personnel with Occupational Exposure to Patient Handling-A Systematic Literature Review and Meta-Analysis.International journal of environmental research and public health · 2020Pooled it
- Article
- Acute Disc Herniation at the Proximal Junctional Segment (UIV/UIV + 1) Following Long Segment Spinal Fusion With Cement-Augmented Instrumentation: A Retrospective Study.International journal of spine surgery · 2026Article
- Reliability of Ultrasonography to Assess Spinal Compression During Heavy Load Carriage.JOR spine · 2026Article
- Sex Hormones Attenuate Pro-Inflammatory Gene Expression in Nucleus Pulposus and Annulus Fibrosus Cells in a Cell-Type Specific Manner.JOR spine · 2026Article
- Association Between Cumulative G-force Exposure and Cervical Spine Degenerative Changes.Military medicine · 2025Article
- Predictive Utility of the Functional Movement Screen and Y-Balance Test: Current Evidence and Future Directions.Sports (Basel, Switzerland) · 2025Review
- List of occupational diseases among farmers in Korea: a literature review.Annals of occupational and environmental medicine · 2025Review
- Sociodemographic Influences on Lumbar Disc Degeneration Severity and the Diagnostic Potential of Disc‑CSF Signal Ratio: Insights from a South East Asia Population Study.Journal of the Belgian Society of Radiology · 2025Article
- Predictive Validity of Multifactorial Injury Risk Models and Associated Clinical Measures in the U.S. Population.Sports (Basel, Switzerland) · 2024Article
- Lumbar spine intervertebral disc desiccation is associated with medical comorbidities linked to systemic inflammation.Archives of orthopaedic and trauma surgery · 2023Article
- Health-related quality of life in patients with low back pain in a low resource setting: a cross-sectional study at a tertiary hospital in Uganda.African health sciences · 2023Article
- Neglected problem: Influence of school bag on lumbar segment in children.Frontiers in pediatrics · 2022Article
- Increasing BMI increases lumbar intervertebral disc deformation following a treadmill walking stress test.Journal of biomechanics · 2021Article
- Characteristics of lumbar disc degeneration and risk factors for collapsed lumbar disc in Korean farmers and fishers.Annals of occupational and environmental medicine · 2021Article
- Intervertebral Disc-on-a-Chip as AdvancedFrontiers in bioengineering and biotechnology · 2021Review
- Finite element investigation on the dynamic mechanical properties of low-frequency vibrations on human L2-L3 spinal motion segments with different degrees of degeneration.Medical & biological engineering & computing · 2020Article
- Computed Tomography Evaluation of Craniovertebral Junction.Journal of neurosciences in rural practice · 2020Article
- Comorbidities associated with cervical spine degenerative disc disease.Journal of orthopaedicsArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are inconsistencies in findings regarding the relationship of occupational loading with spinal degeneration or structural damage. Thus, a systematic review was conducted to determine the current state of knowledge on the association of occupational loading and spine degeneration on imaging.
methodsWe performed electronic searches on MEDLINE, CINAHL and EMBASE. We included cross-sectional, case control and cohort studies evaluating occupational loading as the exposure and lumbar spine structural findings on imaging as the outcomes. When possible, results were pooled.
resultsSeventeen studies were included in the review. Ten studies evaluated the association of occupational loading with disc degeneration (signal intensity), four of which were pooled into a meta-analysis. Of the 10 studies, only two did not identify a relationship between occupation loading and disc degeneration. A meta-analysis including four of the studies demonstrated an association between higher loading and degeneration for all spinal levels, with odds ratios between 1.6 and 3.3. Seven studies evaluated disc height narrowing and seven evaluate disc bulge, with six and five identifying an association of loading and with imaging findings respectively. Three studies evaluated modic changes and one identified and association with occupational load.
conclusionsThere was moderate evidence suggesting a modest association between occupational loading and disc degeneration (signal intensity), and low-quality evidence of an association between occupational loading and disc narrowing and bulging.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.