Evidence map›Paper›PMID 31656057›Full record

Trial reportAddiction (Abingdon, England)2020

Diffusion of effects of the ASSIST school-based smoking prevention intervention to non-participating family members: a secondary analysis of a randomized controlled trial.

James White, Jo Holliday, Rhian Daniel, Rona Campbell, Laurence Moore

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Addiction (Abingdon, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A systematic review of causal pathways of socioeconomic inequalities in stroke.International journal of stroke : official journal of the International Stroke Society · 2026
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

James WhiteCentre for Trials Research, Cardiff University, Neuadd Meirionnydd, Cardiff, UK.ORCID 0000-0001-8371-8453
Jo HollidayNuffield Department of Population Health, Big Data Institute, University of Oxford, Oxford, UK.
Rhian DanielSchool of Medicine, Cardiff University, Neuadd Meirionnydd, Cardiff, UK.
Rona CampbellPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Laurence MooreMRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK.

Funding

Chief Scientist Office SPHSU14Medical Research Council MC_UU_12017/14Medical Research Council MR/K023233/1Wellcome Trust
6 · The paper itself

Abstract

aimsTo investigate whether effects of the ASSIST (A Stop Smoking In Schools Trial) school-based smoking prevention intervention diffused from students to the people they lived with.

designSecondary analysis of a cluster-randomized control trial (cRCT).

settingEngland and Wales.

participantsA total of 10 730 students aged 12-13 years in 59 schools assigned using stratified block randomization to the control (29 schools, 5372 students) or intervention (30 schools, 5358 students) condition. INTERVENTION AND COMPARATOR: The ASSIST intervention involves 2 days of off-site training of influential students to encourage their peers not to smoke during a 10-week period. The control group continued with their usual education. MEASUREMENTS: The outcomes were the proportion of students who self-reported living with a smoker and the smoking status of each resident family member/caregiver. Follow-up assessments were immediately after the intervention and at 1 and 2 years post-intervention.

findingsThe odds ratio (OR) for living with a smoker in the intervention compared with the control groups was 0.86 [95% confidence interval (CI) = 0.72, 1.03] immediately after the intervention, OR = 0.84 (95% CI = 0.72, 0.97) at a 1-year follow-up and OR = 0.86 (95% CI = 0.75, 0.99) at 2-year follow-up. In a three-tier multi-level model with data from all three follow-ups, student-reported smoking by fathers (OR = 0.90, 95% CI = 0.80, 1.00), brothers (OR = 0.78, 95% CI = 0.67, 0.92) and sisters (OR = 0.80, 95% CI = 0.69, 0.92) was lower in the intervention compared with control group. Subgroup analyses by baseline smoking status suggested that these effects were more consistent with prevention of uptake than prompting cessation.

conclusionsA Stop Smoking In Schools Trial (ASSIST) school-based smoking prevention intervention may have reduced the prevalence of smoking in people who lived with ASSIST-trained students. This indirect transmission is consistent with the predictions of diffusion of innovations theory which underpins the design of ASSIST.

Indexed as

AdolescentChildEnglandFamilyFemaleHumansMalePeer GroupPrevalenceProgram EvaluationSchool Health ServicesSchoolsSmokingSmoking CessationSmoking PreventionStudentsDiffusionfamilypeerspreventionsmokingspillover

Identifiers

PMID31656057
PMCPMC7156286

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.