Evidence map›Paper›PMID 31656020›Full record

ReviewPathology oncology research : POR2020

Review: Ewing Sarcoma Predisposition.

Pablo Gargallo, Yania Yáñez, Antonio Juan, Vanessa Segura, Julia Balaguer, Bárbara Torres, Silves Oltra, Victoria Castel, Adela Cañete

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pathology oncology research : POR, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

  1. Ewing sarcoma of the great toe: a rare case report.International journal of surgery case reports · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. [Analysis of 41 cases of non-metastatic Ewing's sarcoma in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Fli1 and Tissue Fibrosis in Various Diseases.International journal of molecular sciences · 2023
    Review
  12. Whole exome sequencing identified a novelFrontiers in oncology · 2022
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Pablo GargalloClinical and Translational Oncology Research Group, La Fe Hospital, Av. Fernando Abril Martorell 106 Postal Code, 46026, Valencia, Spain. gargallo_pabtat@gva.es.ORCID http://orcid.org/0000-0001-9720-8542
Yania YáñezClinical and Translational Oncology Research Group, La Fe Hospital, Av. Fernando Abril Martorell 106 Postal Code, 46026, Valencia, Spain.
Antonio JuanPediatric Oncology and Hematology Unit, La Fe Hospital, Valencia, Spain.
Vanessa SeguraClinical and Translational Oncology Research Group, La Fe Hospital, Av. Fernando Abril Martorell 106 Postal Code, 46026, Valencia, Spain.
Julia BalaguerPediatric Oncology and Hematology Unit, La Fe Hospital, Valencia, Spain.
Bárbara TorresPediatric Oncology and Hematology Unit, La Fe Hospital, Valencia, Spain.
Silves OltraGenetics Unit, La Fe Hospital, Valencia, Spain.
Victoria CastelPediatric Oncology and Hematology Unit, La Fe Hospital, Valencia, Spain.
Adela CañetePediatric Oncology and Hematology Unit, La Fe Hospital, Valencia, Spain.
Hospital Universitari i Politècnic La Fe · ESInstituto de Investigación Sanitaria La Fe · ESUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ewing sarcoma is a rare tumor developed in bone and soft tissues of children and teenagers. This entity is biologically led by a chromosomal translocation, typically including EWS and FLI1 genes. Little is known about Ewing sarcoma predisposition, although the role of environmental factors, ethnicity and certain polymorphisms on Ewing sarcoma susceptibility has been studied during the last few years. Its prevalence among cancer predisposition syndromes has also been thoroughly examined. This review summarizes the available evidence on predisposing factors involved in Ewing sarcoma susceptibility. On the basis of these data, an integrated approach of the most influential factors on Ewing sarcoma predisposition is proposed.

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideBone NeoplasmsHumansProto-Oncogene Protein c-fli-1RNA-Binding Protein EWSSarcoma, EwingEWSR1 protein, humanFLI1 protein, humanProto-Oncogene Protein c-fli-1RNA-Binding Protein EWSCancer predispositionEwing sarcomaGenetic susceptibilityPolymorphism

Identifiers

PMID31656020
OpenAlexW2981794627

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.