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ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2020

Molecular characterization of Mycoplasma pneumoniae infections in Moscow from 2015 to 2018.

Elena N Voronina, Maria A Gordukova, Irina E Turina, Olga V Mishukova, Maya A Dymova, Elena V Galeeva, Anatoliy A Korsunskiy, Maxim L Filipenko

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Analysis ofTranslational pediatrics · 2021
    Article
  6. Increased Macrolide Resistance Rate of M3562Frontiers in cellular and infection microbiology · 2021
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elena N VoroninaLaboratory of Pharmacogenomics, Institute of Chemical Biology and Fundamental Medicine, Lavrentjeva, 8, Novosibirsk, Russia, 630090. voronina_en@niboch.nsc.ru.
Maria A GordukovaMoscow City Pediatric G. Speransky Clinical Hospital, No. 9, Shmitovsky Proezd 29, Moscow, Russia, 123317.
Irina E TurinaThe Federal State Autonomous Educational Institution of Higher Education "The I.M. Sechenov First Moscow State Medical University" of the Ministry of Health of the Russian Federation , Pogodinskaya St. 1, Moscow, Russia, 119991.
Olga V MishukovaLaboratory of Pharmacogenomics, Institute of Chemical Biology and Fundamental Medicine, Lavrentjeva, 8, Novosibirsk, Russia, 630090.
Maya A DymovaLaboratory of Pharmacogenomics, Institute of Chemical Biology and Fundamental Medicine, Lavrentjeva, 8, Novosibirsk, Russia, 630090.
Elena V GaleevaMoscow City Pediatric G. Speransky Clinical Hospital, No. 9, Shmitovsky Proezd 29, Moscow, Russia, 123317.
Anatoliy A KorsunskiyMoscow City Pediatric G. Speransky Clinical Hospital, No. 9, Shmitovsky Proezd 29, Moscow, Russia, 123317.
Maxim L FilipenkoLaboratory of Pharmacogenomics, Institute of Chemical Biology and Fundamental Medicine, Lavrentjeva, 8, Novosibirsk, Russia, 630090.

Funding

Russian State funded budget project of ICBFM SB RAS АААА-А17-117020210027-9
6 · The paper itself

Abstract

The aim of this study was to assess which Mycoplasma pneumoniae genotypes were present in Moscow during the years 2015-2018 and whether the proportion between detected genotypes changed over time. We were also interested in the presence of macrolide resistance (MR)Mycoplasma pneumoniae. We performed multilocus variable-number tandem-repeat (VNTR) analysis (MLVA), SNP typing, and mutation typing in the 23S rRNA gene from 117 M. pneumoniae clinical isolates. Our analysis suggests two major MLVA types: 4572 and 3562. In 2017-2018, MLVA type 4572 gradually became predominant. In general, the SNP type range is the same as described earlier for European countries. The analysis of MR mutations showed that 7% of the isolates had an A2063G mutation in the 23S rRNA gene with no isolates carrying an A2064G mutation. In 2017-2018, MLVA type 4572 (SNP type 1) begins to spread in Moscow, which was widespread globally, especially in Asian countries. SNP typing of our sample showed higher discriminatory power than MLVA typing.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialHistory, 21st CenturyHumansMacrolidesMicrobial Sensitivity TestsMoscowMultilocus Sequence TypingMycoplasma pneumoniaePneumonia, MycoplasmaPolymorphism, Single NucleotidePublic Health SurveillanceRNA, Ribosomal, 23SAnti-Bacterial AgentsMacrolidesRNA, Ribosomal, 23SMacrolide resistanceMLVAMycoplasma pneumoniaeSNP

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.