Evidence map›Paper›PMID 31655851›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2020

Bromelain reversed electrolyte imbalance in the chronically constricted sciatic nerve of Wistar rats.

Ahmed Olalekan Bakare, Bamidele Victor Owoyele

Abstract read
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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Harnessing therapeutic potential of bromelain and its nanoformulations: sojourn of pineapple from food to nanomedicine.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ahmed Olalekan BakarePain and Inflammation Unit, Department of Physiology, University of Ilorin, Ilorin, Kwara State, Nigeria. wlabwise@gmail.com.ORCID http://orcid.org/0000-0003-3936-1228
Bamidele Victor OwoyeleNeuroscience Unit, Department of Physiology, University of Ilorin, Ilorin, Kwara State, Nigeria.
University of Ilorin · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Derangement of electrolyte in the sensory nervous system has been attributed to the development and maintenance of hyperalgesic and allodynic symptoms in painful neuropathy. This study investigated the effect of bromelain on electrolyte imbalance in chronically constricted sciatic nerve of rats (a model of neuropathic pain). Forty Wistar rats, divided into five groups of eight animals each were used for this study. von Frey filaments, tail immersion and acetone spray tests were used to assessed allodynic and thermal hyperalgesic symptoms in the Wistar rats. Sodium ion (Na

Indexed as

AnimalsBromelainsChronic PainConstrictionDose-Response Relationship, DrugMalePain MeasurementRatsRats, WistarSciatic NeuropathyWater-Electrolyte BalanceBromelainsBromelainChronic constriction injuryElectrogenic pumpElectrolyte imbalanceSciatic nerve

Identifiers

PMID31655851
OpenAlexW2982129288

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.