Evidence map›Paper›PMID 31655628›Full record

ArticleBMC research notes2019

Burden of Shigella spp and Vibrio spp, and their antibiotic sensitivity pattern in the patients with acute gastroenteritis in tertiary care hospital in Nepal.

Shiv Kumar Sah, Shreejana Basnet, Sushma Shrestha, Kusum Ghale, Sabita Tamang, Dipendra Kumar Mandal, Sher Bahadur Pun

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shiv Kumar SahFaculty of Pharmaceutical Science, Little Buddha College of Health Science, Purbanchal University, Minbhawan, Kathmandu, Nepal. phrshiv@gmail.com.
Shreejana BasnetFaculty of Pharmaceutical Science, Little Buddha College of Health Science, Purbanchal University, Minbhawan, Kathmandu, Nepal.
Sushma ShresthaFaculty of Pharmaceutical Science, Little Buddha College of Health Science, Purbanchal University, Minbhawan, Kathmandu, Nepal.
Kusum GhaleFaculty of Pharmaceutical Science, Little Buddha College of Health Science, Purbanchal University, Minbhawan, Kathmandu, Nepal.
Sabita TamangFaculty of Pharmaceutical Science, Little Buddha College of Health Science, Purbanchal University, Minbhawan, Kathmandu, Nepal.
Dipendra Kumar MandalSukraraj Tropical and Infectious Disease Hospital, Teku, Nepal.
Sher Bahadur PunSukraraj Tropical and Infectious Disease Hospital, Teku, Nepal.
Purbanchal University · NPSukraraj Tropical & Infectious Disease Hospital · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe present study aims to investigate the etiology, clinical profile and resistance pattern of the isolated pathogens in Nepalese adults with acute gastroenteritis. This cross-sectional study was conducted at Sukraraj Tropical and Infectious Disease Hospital, from April 2016 to Sep 2017. Subjects' ages 14 or above, presenting with gastroenteritis with positive stool culture were enrolled for analysis.

resultsOf total 153 patients, 47.72% subjects confirmed the presence of bacterial infection. Vibrio cholerae spp and Shigella spp were detected in 36.6% and 23.28% respectively. The most common resistance among Vibrio cholerae was to nitrofurantoin (92.8%), cotrimoxazole (92.8%) and nalidixic acid (92.8%). Among 17 isolates of Shigella spp, the most frequent drug resistant was observed in ampicillin (64.7%), nalidixic acid (58.8%), ceftriaxone (47%). Chloramphenicol (94.1%), tetracycline (88.2%), and cotrimoxazole (82.3%) were found to be the most sensitive towards this pathogen. High rate of diarrhea due to bacterial infection, especially Shigella spp and Vibrio spp and their high rate of drug resistance emphasize an urgent need of designing a surveillance system for antimicrobial resistance in Nepalese setting.

Indexed as

Tertiary Care CentersAcute DiseaseAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBacterial InfectionsCross-Sectional StudiesDiarrheaFemaleGastroenteritisHumansMaleMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsAcute gastroenteritisBacterial isolatesClinical profileResistance pattern

Identifiers

PMID31655628
PMCPMC6815351
OpenAlexW2981645945

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.