ArticleTurkish journal of medical sciences2019
Neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, and platelet-tolymphocyte ratio in different etiological causes of thyrotoxicosis
Article in Turkish journal of medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Platelet abnormalities in autoimmune thyroid diseases: A systematic review and meta-analysis.Frontiers in immunology · 2022Pooled it
- Inflammatory Signatures of Graves' Orbitopathy: Linking Thyroid Autoimmunity, Disease Activity, and Novel Hematological Biomarkers.Diagnostics (Basel, Switzerland) · 2026Article
- Mean Platelet Volume Is a Poor Prognostic Factor in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025Article
- Combining biomarkers to predict the disease activity of graves' ophthalmopathy: a combinatory model of the NLR, TRAb and FT4.Frontiers in endocrinology · 2025Article
- Evaluating the Role of CBC-Derived Indices in Children with Hashimoto's Thyroiditis.Diagnostics (Basel, Switzerland) · 2024Article
- Effect of thyroid hormone status on complete blood cell count-derived inflammatory biomarkers in patients with moderate-to-severe Graves' ophthalmopathy.International ophthalmology · 2023Article
- Could the Systemic Immune Inflammation Index Predict Diagnosis, Recovery Time, Hypothyroidism, and Recurrence Rates in Subacute Thyroiditis?International journal of general medicine · 2023Article
- Risk Factors for Granulocytopenia in Patients with Graves' Disease Receiving Antithyroid Drugs.International journal of endocrinology · 2023Article
- The diagnostic value of blood cell-derived indexes in subacute thyroiditis patients with thyrotoxicosis: a retrospective study.Annals of translational medicine · 2022Article
- Early Thyroid Volume Reduction in Subacute Thyroiditis Can be a Potential Indicator for Hypothyroidism.Frontiers in endocrinology · 2022Article
- New aspects in the pathogenesis and management of subacute thyroiditis.Reviews in endocrine & metabolic disorders · 2021Review
- Blood Count-derived Immunoinflammatory Markers in Thyroidassociated Ophthalmopathy.Korean journal of ophthalmology : KJO · 2021Article
- Usefulness of pre-thyroidectomy neutrophil-lymphocyte, platelet-lymphocyte, and monocyte-lymphocyte ratios for discriminating lymph node and distant metastases in differentiated thyroid cancer.Clinics (Sao Paulo, Brazil) · 2021Article
- Higher Serum Lactic Dehydrogenase is Associated with Post-Stroke Depression at Discharge.Clinical interventions in aging · 2021Article
- Neutrophil-to-Lymphocyte, Monocyte-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Relation to Clinical Parameters and Smoking Status in Patients with Graves' Orbitopathy-Novel Insight into Old Tests.Journal of clinical medicine · 2020Article
- A Case of Thyroid Storm Caused by Thyroiditis.Journal of investigative medicine high impact case reportsArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/aim: The most common causes of thyrotoxicosis include Graves’ disease (GD), toxic multinodular goiter (TMNG), toxic adenoma (TA), and subacute granulomatous thyroiditis (SAT). In our study, we aimed to see whether neutrophil‐to‐lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet‐to‐lymphocyte ratio (PLR), and mean platelet volume (MPV) may be helpful in the differential diagnosis of these diseases. Materials and methods: We retrospectively analyzed the hospital records of the Endocrinology Clinic of our hospital between 2016 and 2019. We included data from 66 GD, 37 TA, and 35 SAT patients. We compared the data with those of 35 healthy subjects as controls. Results: NLR, MLR, and PLR were found to be higher in the SAT group when compared to other groups. The post hoc analysis of comparison of NLR, MLR, and PLR in each group showed that NLR and PLR were significantly different in the SAT group when compared to the GD, TA, and controls groups (P < 0.001, P = 0.003, and P < 0.001 for NLR respectively and P < 0.001 for PLR in all groups). MPV levels were different between groups (P = 0.007). However, the intergroup analysis (Tukey’s test) failed to show a statistically significant difference for any of the groups. In patients with SAT, PLR and NLR were significantly higher than in the GD, TA, and control groups. MLR was also higher in SAT when compared to other groups, but the difference was not statistically significant. Conclusion: High PLR and NLR may be helpful to differentiate SAT from GD and TA, the other common causes of thyrotoxicosis.
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