Evidence map›Paper›PMID 31655193›Full record

ArticleLife sciences2019

Exercise does not ameliorate cardiac dysfunction in obese mice exposed to fine particulate matter.

Jacob A Grimmer, Vineeta Tanwar, Dane J Youtz, Jeremy M Adelstein, Stephen H Baine, Cynthia A Carnes, Lisa A Baer, Kristin I Stanford, Loren E Wold

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Heat-not-burn tobacco products: an emerging threat to cardiovascular health.American journal of physiology. Heart and circulatory physiology · 2020
    Review
  2. Cardiovascular adaptations to particle inhalation exposure: molecular mechanisms of the toxicology.American journal of physiology. Heart and circulatory physiology · 2020
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Jacob A GrimmerDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, OH, USA; College of Nursing, The Ohio State University, Columbus, OH, USA.
Vineeta TanwarDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, OH, USA; College of Nursing, The Ohio State University, Columbus, OH, USA.
Dane J YoutzDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, OH, USA; College of Nursing, The Ohio State University, Columbus, OH, USA.
Jeremy M AdelsteinDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, OH, USA; College of Nursing, The Ohio State University, Columbus, OH, USA.
Stephen H BaineCollege of Pharmacy, The Ohio State University, Columbus, OH, USA.
Cynthia A CarnesCollege of Pharmacy, The Ohio State University, Columbus, OH, USA.
Lisa A BaerDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, OH, USA.
Kristin I StanfordDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, OH, USA; Department of Physiology and Cell Biology, The Ohio State University College of Medicine and Wexner Medical Center, Columbus, OH, USA.
Loren E WoldDorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, OH, USA; College of Nursing, The Ohio State University, Columbus, OH, USA; Department of Physiology and Cell Biology, The Ohio State University College of Medicine and Wexner Medical Center, Columbus, OH, USA. Electronic address: Loren.Wold@osumc.edu.
The Ohio State University · USThe Ohio State University Wexner Medical Center · US

Funding

Mechanisms of exposure-induced tissue functional and pathological changes in a mouse model of Alzheimer's DiseaseR01AG057046 · NIA · OHIO STATE UNIVERSITY · PI COMBS, COLIN K, DEL MONTE, FEDERICA · 2017 to 2021
$4.0M
BAT as a therapeutic for the metabolic and cardiac dysfunction with senescence.R01AG060542 · NIA · OHIO STATE UNIVERSITY · PI COEN, PAUL MARTIN, STANFORD, KRISTIN I · 2019 to 2023
$3.0M
A Novel Role for Brown Adipose Tissue Enhance Heart Function and MetabolismR01HL138738 · NHLBI · OHIO STATE UNIVERSITY · PI STANFORD, KRISTIN I · 2017 to 2021
$2.3M
Muscle function and depression-like behavior in a mouse model of cancer fatigueR01NR012618 · NINR · OHIO STATE UNIVERSITY · PI REISER, PETER J, WOLD, LOREN EUGENE · 2012 to 2016
$2.2M
Defining the Impact of E-Cigarettes on Cardiac PathophysiologyR01HL139348 · NHLBI · OHIO STATE UNIVERSITY · PI WOLD, LOREN EUGENE · 2017 to 2020
$1.9M
Synergistic effects of obesity and air pollution on cardiac functionR01ES019923 · NIEHS · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI WOLD, LOREN EUGENE · 2011 to 2015
$1.8M
BAT as a therapeutic for the metabolic and cardiac dysfunction with senescenceR56AG060542 · NIA · OHIO STATE UNIVERSITY · PI STANFORD, KRISTIN I, ZIOLO, MARK T · 2018 to 2018
$450k
NHLBI NIH HHS R01 HL138738NHLBI NIH HHS R01 HL139348NIA NIH HHS R01 AG057046NIA NIH HHS R01 AG060542NIA NIH HHS R56 AG060542NIEHS NIH HHS R01 ES019923NINR NIH HHS R01 NR012618
6 · The paper itself

Abstract

backgroundStudies have demonstrated that exposure to fine particulate matter (PM

methodsObese mice (ob/ob) (leptin deficient, C57BL/6J background) were exposed to either filtered air (FA) or PM

resultsEchocardiography showed increased left ventricular end systolic (LVESd) and diastolic (LVEDd) diameters in PM

conclusionObese mice exposed to PM

Indexed as

Air PollutantsAnimalsCardiovascular DiseasesHeart DiseasesMaleMiceMice, Inbred C57BLMice, ObeseMyocytes, CardiacObesityParticle SizeParticulate MatterPhysical Conditioning, AnimalAir PollutantsParticulate MatterCardiovascular functionExerciseObesityParticulate matterTreadmill

Identifiers

PMID31655193
PMCPMC6898783
OpenAlexW2982046009

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.