Evidence map›Paper›PMID 31655181›Full record

ReviewThe Journal of steroid biochemistry and molecular biology2020

Vitamin D and the intestine: Review and update.

Sylvia Christakos, Shanshan Li, Jessica De La Cruz, Noah F Shroyer, Zachary K Criss, Michael P Verzi, James C Fleet

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of steroid biochemistry and molecular biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 66 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Optimizing eggshell quality in extended laying periods: Insights and strategies.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026
    Review
  6. Article
  7. Review
  8. Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.The Journal of clinical endocrinology and metabolism · 2025 · on this map
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Anti-inflammatory effects of bay laurel (Food science & nutrition · 2024
    Article
  14. Critical Role for 24-Hydroxylation in Homeostatic Regulation of Vitamin D Metabolism.medRxiv : the preprint server for health sciences · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Sylvia ChristakosDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers, The State University of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA. Electronic address: christak@njms.rutgers.edu.
Shanshan LiDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers, The State University of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA.
Jessica De La CruzDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers, The State University of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA.
Noah F ShroyerIntegrative Molecular and Biomedical Sciences Graduate Program, Division of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Zachary K CrissIntegrative Molecular and Biomedical Sciences Graduate Program, Division of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
Michael P VerziDepartment of Genetics, Rutgers University, New Brunswick, NJ 08854, USA.
James C FleetDepartment of Nutrition Science, Purdue University, West Lafayette, IN 47907, USA.
Rutgers, The State University of New Jersey · USBaylor College of Medicine · USPurdue University West Lafayette · US

Funding

Nutrigenomics of Intestinal Vitamin D ActionR01DK112365 · NIDDK · RUTGERS BIOMEDICAL AND HEALTH SCIENCES · PI SYLVIA S CHRISTAKOS, James C. Fleet · 2017 to 2026
$4.2M
Osteoporosis and Molecular Targets of Vitamin DR21AG044552 · NIA · RBHS-NEW JERSEY MEDICAL SCHOOL · PI CHRISTAKOS, SYLVIA S · 2014 to 2015
$354k
NIA NIH HHS R21 AG044552NIDDK NIH HHS R01 DK112365
6 · The paper itself

Abstract

The central role of vitamin D in calcium homeostasis is to increase calcium absorption from the intestine. This article describes the early work that served as the foundation for the initial model of vitamin D mediated calcium absorption. In addition, other research related to the role of vitamin D in the intestine, including those which have challenged the traditional model and the crucial role of specific calcium transport proteins, are reviewed. More recent work identifying novel targets of 1,25(OH)

Indexed as

AnimalsCalciumCalcium-Binding ProteinsCalcium ChannelsGene Expression RegulationHumansIntestinal MucosaIntestinesReceptors, CalcitriolVitamin DVitamin D DeficiencyCalciumCalcium-Binding ProteinsCalcium ChannelsReceptors, CalcitriolVitamin D1,25-dihydroxyvitamin D3Calbindin-DCrypt, SLC30A10IntestinePlasma membrane calcium pump PMCA1bTransient receptor potential vanilloid type-6Villus

Identifiers

PMID31655181
PMCPMC6954280
OpenAlexW2981841546

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.