ArticleBehavioural brain research2020
A time-based intervention to treat impulsivity in male and female rats.
Article in Behavioural brain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Premature release of action sequences in adolescent male rats.Frontiers in behavioral neuroscience · 2026Article
- Using sign tracking to experimentally increase self-control in rats.Journal of the experimental analysis of behavior · 2024Article
- Abbreviated fixed-interval interventions promote self-control in rats.Behavioural processes · 2024Article
- Active and passive waiting in impulsive choice: Effects of fixed-interval and fixed-time delays.Learning & behavior · 2024Article
- Methylphenidate, but not citalopram, decreases impulsive choice in rats performing a temporal discounting task.Frontiers in psychiatry · 2024Article
- Behavioral mechanisms of oxycodone's effects in female and male rats: Reinforcement delay and impulsive choice.Experimental and clinical psychopharmacology · 2023Article
- Mechanisms of impulsive choice: Experiments to explore and models to map the empirical terrain.Learning & behavior · 2023Review
- Selective chemogenetic inactivation of corticoaccumbal projections disrupts trait choice impulsivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Reward maximization assessed using a sequential patch depletion task in a large sample of heterogeneous stock rats.Scientific reports · 2023Article
- Cognitive mechanisms underlying decision making involving risk of explicit punishment in male and female rats.Cognitive, affective & behavioral neuroscience · 2023Article
- Effects of the estrous cycle on impulsive choice and interval timing in female rats.Hormones and behavior · 2023Article
- A behavioral timing intervention upregulates striatal serotonergic markers and reduces impulsive action in adult male mice.Behavioural brain research · 2023Article
- Reward Maximization Assessed Using a Sequential Patch Depletion Task in a Large Sample of Heterogeneous Stock Rats.Research square · 2023Article
- Reducing impulsive choice: VIII. Effects of delay-exposure training in female rats.Behavioural processes · 2022Article
- Generalizability of time-based interventions: Effects of choice procedure and smaller-sooner delay.Behavioural processes · 2022Article
- Hazard function effects on promoting self-control in variable interval time-based interventions in rats.Journal of the experimental analysis of behavior · 2021Article
- Quantifying the contribution of individual variation in timing to delay-discounting.Scientific reports · 2021Article
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5 authors.
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Abstract
Time-based interventions have emerged as promising treatments for disorders associated with impulsivity. These interventions can be implemented to test their efficacy in preventing or treating impulsive choice in animal models of diseases related to impulsivity such as drug abuse. Impulsive choice is typically defined as choosing a smaller-sooner (SS) reward over a larger-later (LL) reward when the LL is relatively more optimal. Previous research has shown that these interventions promote LL choices in males and females, but sex differences have not been assessed. Because sex differences can complicate the application of therapies, it is critical to compare the effects of the intervention in males and females. The intervention group received exposure to 10-s and 30-s interval schedules, and the control rats received no delay to reward. Different impulsive choice tasks were used to assess the intervention efficacy across the two experiments. Following the intervention, reductions in impulsive choice were found in male and female rats, but the degree of improvement was inconsistent across sex and task. Bayesian analyses that combined the results revealed robust evidence of an overall intervention effect with the intervention group showing greater self-control, but there was no evidence for the intervention affecting males and females differently. Taken together, these results suggest that time-based interventions are effective tools to treat impulsivity in both males and females and offer promising translational capability to humans.
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