Evidence map›Paper›PMID 31655095›Full record

ArticleBehavioural brain research2020

Effects of dopamine and serotonin synthesis inhibitors on the ketamine-, d-amphetamine-, and cocaine-induced locomotor activity of preweanling and adolescent rats: sex differences.

Sanders A McDougall, Jasmine W Rios, Matthew G Apodaca, Ginny I Park, Nazaret R Montejano, Jordan A Taylor, Andrea E Moran, Jasmine A M Robinson, Timothy J Baum, Angie Teran and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Behavioural brain research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  7. Use and abuse of dissociative and psychedelic drugs in adolescence.Pharmacology, biochemistry, and behavior · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Sanders A McDougallDepartment of Psychology, California State University, San Bernardino, CA, USA. Electronic address: smcdouga@csusb.edu.
Jasmine W RiosDepartment of Psychology, California State University, San Bernardino, CA, USA.
Matthew G ApodacaDepartment of Psychology, California State University, San Bernardino, CA, USA.
Ginny I ParkDepartment of Psychology, California State University, San Bernardino, CA, USA.
Nazaret R MontejanoDepartment of Psychology, California State University, San Bernardino, CA, USA.
Jordan A TaylorDepartment of Psychology, California State University, San Bernardino, CA, USA.
Andrea E MoranDepartment of Psychology, California State University, San Bernardino, CA, USA; Department of Psychology, University of Nebraska-Lincoln, Lincoln, NE, USA.
Jasmine A M RobinsonDepartment of Psychology, California State University, San Bernardino, CA, USA.
Timothy J BaumDepartment of Psychology, California State University, San Bernardino, CA, USA.
Angie TeranDepartment of Psychology, California State University, San Bernardino, CA, USA.
Cynthia A CrawfordDepartment of Psychology, California State University, San Bernardino, CA, USA.
California State University, San Bernardino · USUniversity of Nebraska–Lincoln · US

Funding

CSU San Bernardino Minority Access to Research CareersT34GM083883 · NIGMS · CALIFORNIA STATE UNIV SAN BERNARDINO · PI MCDOUGALL, SANDERS · 2009 to 2019
$3.0M
CSUSB - DIDARPR24DA033877 · NIDA · CALIFORNIA STATE UNIV SAN BERNARDINO · PI CRAWFORD, CYNTHIA A. · 2012 to 2016
$2.1M
NIDA NIH HHS R24 DA033877NIGMS NIH HHS T34 GM083883
6 · The paper itself

Abstract

The pattern of ketamine-induced locomotor activity varies substantially across ontogeny and according to sex. Although ketamine is classified as an NMDA channel blocker, it appears to stimulate the locomotor activity of both male and female rats via a monoaminergic mechanism. To more precisely determine the neural mechanisms underlying ketamine's actions, male and female preweanling and adolescent rats were pretreated with vehicle, the dopamine (DA) synthesis inhibitor ∝-methyl-

Indexed as

Age Factorsalpha-MethyltyrosineAnimalsBehavior, AnimalCentral Nervous System StimulantsCocaineDextroamphetamineDopamine AgentsDrug InteractionsEnzyme InhibitorsExcitatory Amino Acid AntagonistsFemaleFenclonineKetamineLocomotionMale4-chlorophenylalanine methyl esteralpha-MethyltyrosineCentral Nervous System StimulantsCocaineDextroamphetamineDopamine AgentsEnzyme InhibitorsExcitatory Amino Acid AntagonistsFenclonineKetamineReceptors, N-Methyl-D-AspartateSerotonin Agents4-chloro-dl-phenylalanine methyl ester hydrochloride (PCPA)Cocained-amphetamineKetamineLocomotor activity∝-methyl-dl-p-tyrosine (AMPT)

Identifiers

PMID31655095
PMCPMC6917827
OpenAlexW2981979468

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.