Evidence map›Paper›PMID 31655075›Full record

ReviewNeuroscience and biobehavioral reviews2020

Neuroplasticity in cerebral visual impairment (CVI): Assessing functional vision and the neurophysiological correlates of dorsal stream dysfunction.

Christopher R Bennett, Corinna M Bauer, Emma S Bailin, Lotfi B Merabet

Open access · greenAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 87 citations in OpenAlex.

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  9. Cerebral visual impairment (CVI) overlooked: A retrospective review of missed opportunities to diagnose CVI.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Christopher R BennettMassachusetts Eye and Ear, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, United States.
Corinna M BauerMassachusetts Eye and Ear, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, United States.
Emma S BailinMassachusetts Eye and Ear, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, United States.
Lotfi B MerabetMassachusetts Eye and Ear, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, United States. Electronic address: lotfi_merabet@meei.harvard.edu.
Harvard University · USMassachusetts Eye and Ear Infirmary · US

Funding

Audio-Haptic Virtual Environments for Large-Scale Navigation in the BlindR01EY019924 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI MERABET, LOTFI · 2010 to 2018
$3.5M
Neurophysiological Correlates of Visual Motion Processing in Cerebral Visual ImpairmentR01EY030973 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI Lotfi Merabet · 2020 to 2026
$2.0M
Assessing Spatial Processing Deficits in Cerebral Visual Impairment (CVI) Using Virtual RealityR21EY030587 · NEI · MASSACHUSETTS EYE AND EAR INFIRMARY · PI MERABET, LOTFI · 2019 to 2020
$477k
NEI NIH HHS R01 EY019924NEI NIH HHS R01 EY030973NEI NIH HHS R21 EY030587
6 · The paper itself

Abstract

Cerebral visual impairment (CVI) results from perinatal injury to visual processing structures and pathways and is the most common individual cause of pediatric visual impairment and blindness in developed countries. While there is mounting evidence demonstrating extensive neuroplastic reorganization in early onset, profound ocular blindness, how the brain reorganizes in the setting of congenital damage to cerebral (i.e. retro-geniculate) visual pathways remains comparatively poorly understood. Individuals with CVI exhibit a wide range of visual deficits and, in particular, present with impairments of higher order visual spatial processing (referred to as "dorsal stream dysfunction") as well as object recognition (associated with processing along the ventral stream). In this review, we discuss the need for ongoing work to develop novel, neuroscience-inspired approaches to investigate functional visual deficits in this population. We also outline the role played by advanced structural and functional neuroimaging in helping to elucidate the underlying neurophysiology of CVI, and highlight key differences with regard to patterns of neural reorganization previously described in ocular blindness.

Indexed as

Occipital LobeVision DisordersVisual PathwaysWhite MatterHumansNeuronal PlasticityPattern Recognition, VisualCerebral visual impairmentFunctional brain imagingFunctional visionNeuroplasticityOcular blindnessStructural brain imaging

Identifiers

PMID31655075
PMCPMC6949360
OpenAlexW2981359932

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.