Evidence map›Paper›PMID 31655062›Full record

ArticleiScience2019

Recall Responses from Brain-Resident Memory CD8

Sujata Prasad, Shuxian Hu, Wen S Sheng, Priyanka Chauhan, James R Lokensgard

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Review
  3. bTInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Keeping T cell memories in mind.Trends in immunology · 2022
    Review
  7. The role of antiviral CD8Current opinion in neurobiology · 2022
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Memory CD4Cells · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sujata PrasadNeurovirology Laboratory, Department of Medicine, University of Minnesota, 3-107 Microbiology Research Facility, 689 23(rd) Avenue S.E., Minneapolis, MN 55455, USA.
Shuxian HuNeurovirology Laboratory, Department of Medicine, University of Minnesota, 3-107 Microbiology Research Facility, 689 23(rd) Avenue S.E., Minneapolis, MN 55455, USA.
Wen S ShengNeurovirology Laboratory, Department of Medicine, University of Minnesota, 3-107 Microbiology Research Facility, 689 23(rd) Avenue S.E., Minneapolis, MN 55455, USA.
Priyanka ChauhanNeurovirology Laboratory, Department of Medicine, University of Minnesota, 3-107 Microbiology Research Facility, 689 23(rd) Avenue S.E., Minneapolis, MN 55455, USA.
James R LokensgardNeurovirology Laboratory, Department of Medicine, University of Minnesota, 3-107 Microbiology Research Facility, 689 23(rd) Avenue S.E., Minneapolis, MN 55455, USA. Electronic address: loken006@umn.edu.

Funding

Role of B-cells and CNS antibodies in modulating chronic microglial activationR01NS038836 · NINDS · UNIVERSITY OF MINNESOTA · PI LOKENSGARD, JAMES R · 2000 to 2022
$7.3M
T lymphocyte-induced glial activation during CNS immune reconstitution diseaseR01MH066703 · NIMH · UNIVERSITY OF MINNESOTA TWIN CITIES · PI LOKENSGARD, JAMES R · 2003 to 2023
$6.9M
NIMH NIH HHS R01 MH066703NINDS NIH HHS R01 NS038836
6 · The paper itself

Abstract

HIV-associated neurocognitive disorders (HAND) persist even during effective combination antiretroviral therapy (cART). Although the cause of HAND is unknown, studies link chronic immune activation, neuroinflammation, and cerebrospinal fluid viral escape to disease progression. In this study, we tested the hypothesis that specific, recall immune responses from brain-resident memory T cells (bT

Indexed as

Immune System DisorderImmunologyNeuroscienceVirology

Identifiers

PMID31655062
PMCPMC6807101

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.