Evidence map›Paper›PMID 31654456›Full record

ArticleJournal of veterinary internal medicine2019

Immunoglobulin G4-related disease in a dog.

Lydia J Colopy, Kai-Biu Shiu, Laura A Snyder, Anne C Avery, Emily D Rout, A R Moore

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. A series of heterogeneous lymphoproliferative diseases with CD3 and MUM1 co-expressed in cats and dogs.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2023
    Article
  8. The odds of neoplasia in dogs with and without diabetes mellitus.Journal of veterinary internal medicine · 2022
    Article
  9. Article
  10. Article
  11. Progressive gammopathy and coagulopathy in a young English bulldog.The Canadian veterinary journal = La revue veterinaire canadienne · 2021
    Article
  12. Polyclonal B-cell lymphocytosis in English bulldogs.Journal of veterinary internal medicine · 2020
    Article
  13. Article
  14. Immunoglobulin G4-related disease in a dog.Journal of veterinary internal medicine · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Lydia J ColopyVeterinary Emergency Service, Veterinary Specialty Center, Middleton, Wisconsin.ORCID https://orcid.org/0000-0002-8955-117X
Kai-Biu ShiuVeterinary Emergency Service, Veterinary Specialty Center, Middleton, Wisconsin.
Laura A SnyderVeterinary Services, Marshfield Labs, Marshfield, Wisconsin.
Anne C AveryDepartment of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Science, Colorado State University, Fort Collins, Colorado.
Emily D RoutDepartment of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Science, Colorado State University, Fort Collins, Colorado.ORCID https://orcid.org/0000-0003-1435-8532
A R MooreDepartment of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Science, Colorado State University, Fort Collins, Colorado.ORCID https://orcid.org/0000-0003-4904-8788
Colorado State University · USVeterinary Medical Center · JPMarshfield Clinic · US

Funding

Biomedical Research Training for VeterinariansT32OD010437 · OD · COLORADO STATE UNIVERSITY · PI Gregg A Dean, KELLY S SANTANGELO · 2012 to 2026
$6.2M
NIH HHS T32 OD010437
6 · The paper itself

Abstract

Immunoglobulin G4-related disease (IgG4-RD), which affects many organ systems, has been recognized as a distinct clinical entity in human medicine for just over a decade but has not been previously identified in dogs. In humans, IgG4-RD is characterized by diffuse IgG4-positive lymphoplasmacytic infiltrates that commonly lead to increased serum concentrations of IgG4 and IgE, peripheral eosinophilia, tumorous swellings that often include the parotid salivary glands, obliterative phlebitis, and extensive fibrosis. Herein we describe the diagnosis, clinical progression, and successful treatment of IgG4-RD in an 8-year-old female spayed Husky mixed breed dog. Immunoglobulin G4-related disease should be considered as a differential diagnosis for dogs with vague clinical signs, lymphoplasmacytic swellings, restricted polyclonal gammopathy, eosinophilia or some combination of these findings.

Indexed as

AnimalsDog DiseasesDogsFemaleImmunoglobulin GImmunoglobulin G4-Related DiseaseImmunoglobulin GeosinophiliaIgEIgG-Dimmunofixation

Identifiers

PMID31654456
PMCPMC6872619
OpenAlexW2981454200

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.