ArticleJournal of molecular neuroscience : MN2020
The rs12826786 in HOTAIR lncRNA Is Associated with Risk of Autism Spectrum Disorder.
Article in Journal of molecular neuroscience : MN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- The Genetic Landscape of Autism in Iran: A Systematic Review.Iranian journal of psychiatry · 2026Review
- Regulatory Functions of Long Non-coding RNAs and Circular RNAs in the Molecular Pathogenesis of Autism Spectrum Disorder.Cellular and molecular neurobiology · 2025Review
- Non-Coding RNAs in Neurodevelopmental Disorders-From Diagnostic Biomarkers to Therapeutic Targets: A Systematic Review.Biomedicines · 2025Review
- Key Non-coding Variants in Three Neuroapoptosis and Neuroinflammation-Related LncRNAs Are Protectively Associated with Susceptibility to Parkinson's Disease and Some of Its Clinical Features.Molecular neurobiology · 2024Article
- The multifaceted functions of long non-coding RNAExpert reviews in molecular medicine · 2024Review
- Roles of HOTAIR Long Non-coding RNA in Gliomas and Other CNS Disorders.Cellular and molecular neurobiology · 2024Review
- Dissecting the Relationship Between Neuropsychiatric and Neurodegenerative Disorders.Molecular neurobiology · 2023Review
- Emerging Role of Non-coding RNAs in Autism Spectrum Disorder.Journal of molecular neuroscience : MN · 2022Review
- Genetic and molecular biology of autism spectrum disorder among Middle East population: a review.Human genomics · 2021Review
- The Epigenome in Neurodevelopmental Disorders.Frontiers in neuroscience · 2021Review
- Association of HOTAIR Polymorphisms with Susceptibility to Psoriasis in a Chinese Han Population.BioMed research international · 2021Article
- Critical regulation of a NDIME/MEF2C axis in embryonic stem cell neural differentiation and autism.EMBO reports · 2020Article
- Association Analysis Between the rs1899663 Polymorphism of HOTAIR and Risk of Psychiatric Conditions in an Iranian Population.Journal of molecular neuroscience : MN · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autism spectrum disorder (ASD) encompasses a group of neurodevelopmental disorders with complex pattern of inheritance. Several single nucleotide polymorphisms (SNPs) within coding or non-coding regions of genome have been associated with risk of this disorder. In the current study, we genotyped rs12826786, rs1899663, and rs4759314 SNPs within HOX transcript antisense RNA (HOTAIR) in 427 ASD cases and 430 normally developed children. The rs12826786 was associated with ASD in allelic (T vs. C: OR (95% CI) = 1.29 (1.07-1.57), adjusted P value = 0.03) and recessive (TT vs. TC + CC: OR (95% CI) = 1.60 (1.10-2.32), adjusted P value = 0.04) models. However, the other SNPs were not associated with ASD in any inheritance model. No estimated haplotype within HOTAIR was associated with risk of ASD in the assessed population. Based on the results of the current investigation, the rs12826786 can be regarded as a risk locus for ASD in Iranian population.
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