Evidence map›Paper›PMID 31654185›Full record

ArticleMolecular and cellular biochemistry2020

Overexpression of Shrm4 promotes proliferation and differentiation of neural stem cells through activation of GABA signaling pathway.

Runhui Tian, Kaimin Guo, Bo Wu, Hongbo Wang

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Molecular and cellular biochemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Gene Expression of GABABrain sciences · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Runhui TianDepartment of Psychology, The First Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Kaimin GuoDepartment of Andrology, The First Hospital of Jilin University, Changchun, 130021, People's Republic of China.
Bo WuDepartment of Psychology, The Sixth People's Hospital of Changchun, Changchun, 130000, People's Republic of China.
Hongbo WangDepartment of Pediatric Respiratory Disease, The First Hospital of Jilin University, No. 71 Xinmin Street, Changchun, 130021, Jilin Province, People's Republic of China. wanghongbo@jlu.edu.cn.ORCID http://orcid.org/0000-0001-6396-5473
Jilin University · CNSixth Hospital of Changchun City · CN

Funding

National Natural Science Foundation of China No. 81901534
6 · The paper itself

Abstract

Shrm4 is a protein that is exclusively expressed in polarized tissues. The physiological function of Shrm4 in the brain was required to be elucidated. Thus, we aimed to explore how the Shrm4-mediated gamma-aminobutyric acid (GABA) pathway affected neural stem cells (NSCs). At first, the Nestin expression in cultured NSCs was identified. After determination of the interaction of Shrm4 and GABA

Indexed as

Cell DifferentiationCell ProliferationGene Expression RegulationSignal TransductionAnimalsbcl-2-Associated X Proteingamma-Aminobutyric AcidMiceMicrofilament ProteinsNeural Stem CellsProto-Oncogene Proteins c-bcl-2Receptors, GABA-BBax protein, mousebcl-2-Associated X ProteinBcl2 protein, mousegamma-Aminobutyric AcidMicrofilament ProteinsProto-Oncogene Proteins c-bcl-2Receptors, GABA-BBaclofenCGP54626DifferentiationGABAB1Neural stem cellsProliferationShrm4

Identifiers

PMID31654185
OpenAlexW2982064490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.