Evidence map›Paper›PMID 31654146›Full record

ArticleNanoscale research letters2019

Synthesis of Gold Nanoparticles Using Mimosa tenuiflora Extract, Assessments of Cytotoxicity, Cellular Uptake, and Catalysis.

Ericka Rodríguez-León, Blanca E Rodríguez-Vázquez, Aarón Martínez-Higuera, César Rodríguez-Beas, Eduardo Larios-Rodríguez, Rosa E Navarro, Ricardo López-Esparza, Ramón A Iñiguez-Palomares

Open access · goldAbstract read
In one paragraph

Article in Nanoscale research letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 132 citations in OpenAlex.

  1. Article
  2. Gold Nanoparticles for Wound Healing in Animal Models.Nanomaterials (Basel, Switzerland) · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Antibiotics (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
  14. Green synthesis of gold and silver nanoparticles using crude extract ofFrontiers in bioengineering and biotechnology · 2023
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ericka Rodríguez-LeónPhysics Department, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Blanca E Rodríguez-VázquezPolymer and Material Department, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Aarón Martínez-HigueraPhysics Department, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
César Rodríguez-BeasPhysics Department, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Eduardo Larios-RodríguezChemical Engineering and Metallurgy Department, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Rosa E NavarroPolymer and Material Department, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Ricardo López-EsparzaPhysics Department, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico.
Ramón A Iñiguez-PalomaresPhysics Department, University of Sonora, Rosales and Transversal, 83000, Hermosillo, Sonora, Mexico. ramonalfonso.iniguez@gmail.com.ORCID http://orcid.org/0000-0002-9218-936X
Universidad de Sonora · MX

Funding

CONACYT 2018-000005-01NACV-01367
6 · The paper itself

Abstract

Synthesis of gold nanoparticles (AuNPs) with plant extracts has gained great interest in the field of biomedicine due to its wide variety of health applications. In the present work, AuNPs were synthesized with Mimosa tenuiflora (Mt) bark extract at different metallic precursor concentrations. Mt extract was obtained by mixing the tree bark in ethanol-water. The antioxidant capacity of extract was evaluated using 2,2-diphenyl-1-picrylhydrazyl and total polyphenol assay. AuNPs were characterized by transmission electron microscopy, X-ray diffraction, UV-Vis and Fourier transform infrared spectroscopy, and X-ray photoelectron spectrometry for functional group determination onto their surface. AuMt (colloids formed by AuNPs and molecules of Mt) exhibit multiple shapes with sizes between 20 and 200 nm. AuMt were tested on methylene blue degradation in homogeneous catalysis adding sodium borohydride. The smallest NPs (AuMt1) have a degradation coefficient of 0.008/s and reach 50% degradation in 190s. Cell viability and cytotoxicity were evaluated in human umbilical vein endothelial cells (HUVEC), and a moderate cytotoxic effect at 24 and 48 h was found. However, toxicity does not behave in a dose-dependent manner. Cellular internalization of AuMt on HUVEC cells was analyzed by confocal laser scanning microscopy. For AuMt1, it can be observed that the material is dispersed into the cytoplasm, while in AuMt2, the material is concentrated in the nuclear periphery.

Indexed as

CatalysisCellular uptakeGoldNanoparticles

Identifiers

PMID31654146
PMCPMC6814701
OpenAlexW2981528867

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.