Evidence map›Paper›PMID 31653894›Full record

ArticleScientific reports2019

IL-21 regulates SOCS1 expression in autoreactive CD8

Andrew P R Sutherland, Kate L Graham, Michelle Papadimitriou, Gaurang Jhala, Prerak Trivedi, Tara Catterall, Stacey Fynch, Thomas W H Kay, Helen E Thomas

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. JAK inhibitors: a new choice for diabetes mellitus?Diabetology & metabolic syndrome · 2025
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Andrew P R SutherlandSt Vincent's Institute of Medical Research, Melbourne, Australia. asutherland@svi.edu.au.ORCID http://orcid.org/0000-0003-0366-9327
Kate L GrahamSt Vincent's Institute of Medical Research, Melbourne, Australia.
Michelle PapadimitriouSt Vincent's Institute of Medical Research, Melbourne, Australia.
Gaurang JhalaSt Vincent's Institute of Medical Research, Melbourne, Australia.
Prerak TrivediSt Vincent's Institute of Medical Research, Melbourne, Australia.
Tara CatterallSt Vincent's Institute of Medical Research, Melbourne, Australia.
Stacey FynchSt Vincent's Institute of Medical Research, Melbourne, Australia.
Thomas W H KaySt Vincent's Institute of Medical Research, Melbourne, Australia.
Helen E ThomasSt Vincent's Institute of Medical Research, Melbourne, Australia. hthomas@svi.edu.au.
The University of Melbourne · AUSt Vincents Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In type 1 diabetes, maturation of activated autoreactive CD8

Indexed as

AnimalsCD8-Positive T-LymphocytesCell DifferentiationCell ProliferationCells, CulturedDiabetes Mellitus, Type 1HumansInterleukin-21InterleukinsIslets of LangerhansMice, Inbred C57BLMice, Inbred NODMice, KnockoutMice, TransgenicSuppressor of Cytokine Signaling 1 ProteinT-Lymphocytes, CytotoxicInterleukin-21InterleukinsSuppressor of Cytokine Signaling 1 Protein

Identifiers

PMID31653894
PMCPMC6814838
OpenAlexW2981648995

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.