Trial reportScientific reports2019
Repeatability and comparison of new Corvis ST parameters in normal and keratoconus eyes.
Trial report in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 79 citations in OpenAlex.
- Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population.Scientific reports · 2021Trial
- Biomechanical changes in keratoconus after customized stromal augmentation.Taiwan journal of ophthalmologyTrial
- Incremental contribution of Corvis ST dynamic biomechanical parameters to interpretable machine learning prediction of clinician-selected refractive procedures: a retrospective observational study.BMC ophthalmology · 2026Observational
- Regional Dependence of Corvis ST Biomechanical Parameters on Corneal Material Properties: A Finite Element Study.Bioengineering (Basel, Switzerland) · 2026Article
- Obesity and Keratoconus: A Mediation Study Based on the Chinese Keratoconus Cohort.Translational vision science & technology · 2026Article
- Comparative assessment of corneal biomechanical parameters in lactating versus non-lactating women: implications for refractive surgery candidates.International ophthalmology · 2026Article
- CorvisThe British journal of ophthalmology · 2026Article
- Long-term comparison of posterior capsular opacification in highly myopic eyes between hydrophilic and hydrophobic intraocular lenses.BMC ophthalmology · 2026Article
- Investigating intraocular pressure fluctuations using corneal visualization Scheimpflug technology tonometry (CST) with varied resting intervals.Frontiers in medicine · 2026Article
- Corneal Biomechanics in Glaucoma: Current Evidence for Diagnosis, Risk Stratification, and Prognosis.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- The influence of corneal biomechanical factors on surgically induced corneal astigmatism.Scientific reports · 2025Article
- Diurnal variations in corneal biomechanics in healthy young adults.BMC ophthalmology · 2025Article
- Correlation between corneal biomechanical and tomographic parameters in cataract patients.International journal of ophthalmology · 2025Article
- Mediating roles of corneal biomechanical and topographic parameters in eye rubbing and keratoconus based on the Chinese keratoconus cohort study.Frontiers in bioengineering and biotechnology · 2025Article
- A New Biomechanical Deformation Response Parameter: Change in Central Corneal Thickness During Air Puff Induced Corneal Deformation.Current eye research · 2024Article
- Keratectasia severity staging and progression assessment based on the biomechanical E-staging.Eye and vision (London, England) · 2024Review
- The Chinese keratoconus (CKC) cohort study.European journal of epidemiology · 2024Article
- Keratoconus cone location influences ocular biomechanical parameters measured by the Ocular Response Analyzer.Eye and vision (London, England) · 2024Article
- Corneal biomechanics in normal and subclinical keratoconus eyes.BMC ophthalmology · 2023Article
- [Corneal biomechanics before and after cross-linking in patients with keratoconus].Die Ophthalmologie · 2023Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To evaluate the repeatability of corneal biomechanical parameters in normal and keratoconus eyes, and explore factors that affects the repeatability, and further assess the diagnostic ability of new parameters. Seventy-seven keratoconus eyes of 47 patients and 77 right eyes of 77 normal subjects were recruited in current study. All participants received three repeated measurements with 2 to 5 minutes interval. The interclass correlation coefficient (ICC), Cronbach' α and repeatability coefficient (RC) were evaluated. The liner regression analysis was used to identify factors that affect the repeatability, and linear mixed effects model was performed to compare the parameters differences. The receiver operating characteristic (ROC) curve was used to evaluate the diagnostic ability of new parameters. Eighteen parameters in normal eyes and twenty-two parameters in keratoconus eyes showed excellent repeatability (ICC ≥ 0.90). Age, axial measurement (AL), spherical equivalent, astigmatism, gender, mean keratometry (Kmean), intraocular pressure (IOP) and central corneal thickness (CCT) could affect the repeatability of new Corvis ST parameters. Compared with normal eyes, the Ambrósio's Relational Thickness horizontal (ARTh), biomechanical corrected IOP (bIOP), stiffness parameter at first applanation (SP A1) were low and the Max Inverse Radius, deformation amplitude (DA) Ratio Max [2 mm], Pachy Slope, DA Ratio Max [1 mm], Integrated Radius and Corvis Biomechanical Index (CBI) were high in keratoconus eyes (All P < 0.05). Both ARTh and CBI had high Youden index (0.870), and the corresponding cut-off values were 379.29 and 0.44. The repeatability of Corvis ST parameters was acceptable both in normal and keratoconus eyes, and new parameters could effectively diagnose keratoconus eyes from normal eyes.
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