Evidence map›Paper›PMID 31653852›Full record

ArticleNature communications2019

Orbitofrontal signals for two-component choice options comply with indifference curves of Revealed Preference Theory.

Alexandre Pastor-Bernier, Arkadiusz Stasiak, Wolfram Schultz

Abstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Neuronal Activity in Orbitofrontal Cortex during Trinary Choices under Risk.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Article
  4. Is the Whole the Sum of its Parts? Neural Computation of Consumer Bundle Valuation in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  5. Prefrontal Default Mode Network Interactions with Posterior Hippocampus during Exploration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Neuronal Activity in the Gustatory Cortex during Economic Choice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The nematode wormeLife · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexandre Pastor-BernierDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3DY, UK.ORCID http://orcid.org/0000-0002-8865-6551
Arkadiusz StasiakDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3DY, UK.ORCID http://orcid.org/0000-0002-7953-4739
Wolfram SchultzDepartment of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3DY, UK. ws234@cam.ac.uk.ORCID http://orcid.org/0000-0002-8530-4518

Funding

The Neurobiology of Social Decision-Making: Social Inference and ContextP50MH094258 · NIMH · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI ADOLPHS, RALPH · 2012 to 2021
$18.6M
NIMH NIH HHS P50 MH094258Wellcome Trust 204811/Z/16/Z
6 · The paper itself

Abstract

Economic choice options contain multiple components and constitute vectorial bundles. The question arises how they are represented by single-dimensional, scalar neuronal signals that are suitable for economic decision-making. Revealed Preference Theory provides formalisms for establishing preference relations between such bundles, including convenient graphic indifference curves. During stochastic choice between bundles with the same two juice components, we identified neuronal signals for vectorial, multi-component bundles in the orbitofrontal cortex of monkeys. A scalar signal integrated the values from all bundle components in the structured manner of the Theory; it followed the behavioral indifference curves within their confidence limits, was indistinguishable between differently composed but equally revealed preferred bundles, predicted bundle choice and complied with an optimality axiom. Further, distinct signals in other neurons coded the option components separately but followed indifference curves as a population. These data demonstrate how scalar signals represent vectorial, multi-component choice options.

Indexed as

Behavior, AnimalAnimalsChoice BehaviorDecision MakingMacaca mulattaModels, TheoreticalNeuronsPrefrontal CortexRewardStochastic Processes

Identifiers

PMID31653852
PMCPMC6814743

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.