Evidence map›Paper›PMID 31653682›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

cAMP Response Element Modulator α Induces Dual Specificity Protein Phosphatase 4 to Promote Effector T Cells in Juvenile-Onset Lupus.

Sigrun R Hofmann, Katrin Mäbert, Franz Kapplusch, Susanne Russ, Sarah Northey, Michael W Beresford, George C Tsokos, Christian M Hedrich

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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  3. Article
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  5. Neuropeptidergic Input from the Lateral Hypothalamus to the Suprachiasmatic Nucleus Alters the Circadian Period in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Review
  11. Dual-Specificity Phosphatases and Kidney Diseases.Kidney diseases (Basel, Switzerland) · 2022
    Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Sigrun R HofmannKlinik und Poliklinik für Kinder- und Jugendmedizin, Universitätsklinikum Carl Gustav Carus, TU Dresden, D01307 Dresden, Germany.ORCID 0000-0003-3128-1143
Katrin MäbertKlinik und Poliklinik für Kinder- und Jugendmedizin, Universitätsklinikum Carl Gustav Carus, TU Dresden, D01307 Dresden, Germany.
Franz KappluschDepartment of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool L14 5AB, United Kingdom.
Susanne RussKlinik und Poliklinik für Kinder- und Jugendmedizin, Universitätsklinikum Carl Gustav Carus, TU Dresden, D01307 Dresden, Germany.
Sarah NortheyDepartment of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool L14 5AB, United Kingdom.
Michael W BeresfordDepartment of Women's and Children's Health, Institute of Translational Medicine, University of Liverpool, Liverpool L14 5AB, United Kingdom.ORCID 0000-0002-5400-9911
George C TsokosDivision of Rheumatology and Clinical Immunology, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215.ORCID 0000-0001-9589-2360
Christian M HedrichKlinik und Poliklinik für Kinder- und Jugendmedizin, Universitätsklinikum Carl Gustav Carus, TU Dresden, D01307 Dresden, Germany; christian.hedrich@liverpool.ac.uk.ORCID 0000-0002-1295-6179
University of Liverpool · GBKlinik und Poliklinik für Kinder- und Jugendmedizin · DEBeth Israel Deaconess Medical Center · US

Funding

Gene transcription in SLER37AI049954 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI TSOKOS, GEORGE C · 2013 to 2022
$4.8M
NIAID NIH HHS R37 AI049954
6 · The paper itself

Abstract

Effector CD4

Indexed as

CD4-Positive T-LymphocytesCyclic AMP Response Element ModulatorDual-Specificity PhosphatasesHumansJurkat CellsLupus Erythematosus, SystemicMitogen-Activated Protein Kinase PhosphatasesSpecies SpecificityCyclic AMP Response Element ModulatorDual-Specificity PhosphatasesDUSP4 protein, humanMitogen-Activated Protein Kinase Phosphatases

Identifiers

PMID31653682
PMCPMC6864280
OpenAlexW2982069921

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.