Evidence map›Paper›PMID 31653508›Full record

ArticleJournal of biomechanics2020

Intervertebral range of motion characteristics of normal cervical spinal segments (C0-T1) during in vivo neck motions.

Chaochao Zhou, Haiming Wang, Cong Wang, Tsung-Yuan Tsai, Yan Yu, Peter Ostergaard, Guoan Li, Thomas Cha

Open access · greenAbstract read
In one paragraph

Article in Journal of biomechanics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Radiograph-based intervertebral sagittal translation-to-canal diameter ratio as a quantitative imaging marker for suspected lower cervical instability.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. Approach to assess the effect of sagittal cervical alignment on three-dimensional movement of the cervical spine in spondylosis patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Chaochao ZhouOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital, Harvard Medical School, Newton, MA, USA; Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Haiming WangOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital, Harvard Medical School, Newton, MA, USA; Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Spinal Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Cong WangSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China.
Tsung-Yuan TsaiSchool of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China. Electronic address: tytsai@sjtu.edu.cn.
Yan YuOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital, Harvard Medical School, Newton, MA, USA; Department of Spine Surgery, Tongji Hospital, Tongji University School of Medicine, Shanghai, China.
Peter OstergaardDepartment of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Guoan LiOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital, Harvard Medical School, Newton, MA, USA. Electronic address: gli1@partners.org.
Thomas ChaOrthopaedic Bioengineering Research Center, Newton-Wellesley Hospital, Harvard Medical School, Newton, MA, USA; Department of Orthopaedic Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Harvard University · USShanghai Jiao Tong University · CNTongji University · CN

Funding

Evaluating adjacent segment biomechanics after ACDF or TDR surgery in cervical spondylosis patients.R03AG056897 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI CHA, THOMAS D · 2018 to 2019
$128k
NIA NIH HHS R03 AG056897
6 · The paper itself

Abstract

The in vivo intervertebral range of motion (ROM) is an important predictor for spinal disorders. While the subaxial cervical spine has been extensively studied, the motion characteristics of the occipito-atlantal (C0-1) and atlanto-axial (C1-2) cervical segments were less reported due to technical difficulties in accurate imaging of these two segments. In this study, we investigated the intervertebral ROMs of the entire cervical spine (C0-T1) during in vivo functional neck motions of asymptomatic human subjects, including maximal flexion-extension, left-right lateral bending, and left-right axial torsion, using previously validated dual fluoroscopic imaging and model registration techniques. During all neck motions, C0-1, similar to C7-T1, was substantially less mobile than other segments and always contributed less than 10% of the cervical rotations. During the axial rotation of the neck, C1-2 contributed 73.2 ± 17.3% of the cervical rotation, but each of other segments contributed less than 10% of the cervical rotation. During both lateral bending and axial torsion neck motions, regardless of primary or coupled motions, the axial torsion ROM of C1-2 was significantly greater than its lateral bending ROM (p < 0.001), whereas the opposite differences were consistently observed at subaxial segments. This study reveals that there are distinct motion patterns at upper and lower cervical segments during in vivo neck motions. The reported data could be useful for the development of new diagnosis methods of cervical pathologies and new surgical techniques that aim to restore normal cervical segmental motion.

Indexed as

MovementRange of Motion, ArticularAdultBiomechanical PhenomenaCervical VertebraeFluoroscopyHumansMaleNeckAtlanto-axial cervical segmentCervical spineIntervertebral range of motionIn vivo neck motionsOccipito-atlantal cervical segmentSpinal kinematicsSubaxial cervical segments

Identifiers

PMID31653508
PMCPMC6938025
OpenAlexW2981296042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.