Evidence map›Paper›PMID 31653150›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2019

Replacing Iodine Staining with Size of Lesion: The Performance of Modified Reid Colposcopic Index.

Sathone Boonlikit, Pornrapee Arnont

Open access · goldAbstract read
In one paragraph

Article in Asian Pacific journal of cancer prevention : APJCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 82% of its field
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sathone BoonlikitDivision of Gynecologic Oncology, Department of Obstetrics and Gynecology, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand.
Pornrapee ArnontDepartment of Obstetrics and Gynecology, Pathum Thani Hospital, Pathum Thani, Thailand.
Rangsit University · THUdon Thani Hospital · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis study of diagnostic accuracy aimed to assess the performance of authors' proposing colposcopic index for detecting histological diagnosis of cervical intraepithelial neoplasia grade 2 or worse (CIN2 or worse).

methodsRetrospective analysis of data was carried out on medical records of women who underwent colposcopy in Rajavithi hospital from January 2007 to December 2014. The authors' proposed score included the first 3 criteria of RCI (margin, color, vascular pattern) and replacing the last RCI criterion (iodine staining) with the detail of size and location of a lesion which was retrospectively retrieved from medical records. Total score for detecting any lesion was ranged from 0-8, similar to the RCI. Performance of the score was assessed for sensitivity, specificity, and positive and negative predictive values at every cut-off level.

resultsAmong 207 eligible women, 87 (42%) had CIN2 or worse. Cut-off level of score ≥ 6 had a sensitivity, specificity, and positive and negative predictive values of 54.0%,97.5%,94.0%,74.5%, respectively while cut-off value ≥ 2 had sensitivity , specificity, positive and negative predictive values of 94.2% ,55.8% ,60.7%, and 93.0%, respectively, for histological diagnosis of CIN 2 or worse. The area under ROC curve was 0.88. In women with type 3 T-zone, the area under ROC curve was 0.94 which was excellent.

conclusionThe performance of the colposcopic score that replaces iodine staining with the size and location of the lesion is good and practical. High cut-off level can be used in see and treat approach for high-grade squamous intraepithelial lesions. Low cut-off level may be used for omitting biopsy in case of low grade impression. This scoring system seems to have greater performance in womens with type 3 T- zone.

Indexed as

AdolescentAdultAgedAged, 80 and overColposcopyFemaleFollow-Up StudiesHumansIodineMiddle AgedPrognosisRetrospective StudiesROC CurveStaining and LabelingUterine Cervical DysplasiaUterine Cervical NeoplasmsIodineColposcopic indexcolposcopySwede colposcopic score

Identifiers

PMID31653150
PMCPMC6982656
OpenAlexW2981554849

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.