Evidence map›Paper›PMID 31653119›Full record

ReviewInternational journal of molecular sciences2019

Pathophysiology of Calcium Mediated Ventricular Arrhythmias and Novel Therapeutic Options with Focus on Gene Therapy.

Vera Paar, Peter Jirak, Robert Larbig, Naufal Shamilevich Zagidullin, Mathias C Brandt, Michael Lichtenauer, Uta C Hoppe, Lukas J Motloch

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. ArrhythmoGenoPharmacoTherapy.Frontiers in pharmacology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Vera PaarDepartment of Internal Medicine II, Paracelsus Medical University, 5020 Salzburg, Austria. v.paar@salk.at.
Peter JirakDepartment of Internal Medicine II, Paracelsus Medical University, 5020 Salzburg, Austria. p.jirak@salk.at.
Robert LarbigDivision of Cardiology, Hospital Maria Hilf Moenchengladbach, 41063 Moenchengladbach, Germany. robert.larbig@mariahilf.de.
Naufal Shamilevich ZagidullinDepartment of Internal Diseases, Bashkir State Medical University, 450000 Ufa, Russia. nau36@yahoo.com.
Mathias C BrandtDepartment of Internal Medicine II, Paracelsus Medical University, 5020 Salzburg, Austria. m.brandt@salk.at.
Michael LichtenauerDepartment of Internal Medicine II, Paracelsus Medical University, 5020 Salzburg, Austria. m.lichtenauer@salk.at.
Uta C HoppeDepartment of Internal Medicine II, Paracelsus Medical University, 5020 Salzburg, Austria. u.hoppe@salk.at.
Lukas J MotlochDepartment of Internal Medicine II, Paracelsus Medical University, 5020 Salzburg, Austria. l.motloch@salk.at.
Paracelsus Medical University · ATBashkir State Medical University · RUKliniken Maria Hilf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac arrhythmias constitute a major health problem with a huge impact on mortality rates and health care costs. Despite ongoing research efforts, the understanding of the molecular mechanisms and processes responsible for arrhythmogenesis remains incomplete. Given the crucial role of Ca

Indexed as

Genetic TherapyAnimalsArrhythmias, CardiacCalciumCalcium ChannelsHumansReceptors, Adrenergic, betaRNA, Small InterferingRyanodine Receptor Calcium Release ChannelSarcoplasmic Reticulum Calcium-Transporting ATPasesCalciumCalcium ChannelsReceptors, Adrenergic, betaRNA, Small InterferingRyanodine Receptor Calcium Release ChannelSarcoplasmic Reticulum Calcium-Transporting ATPasescalciumgene therapygenetic mutationsheart failureion channelsL-type calcium channelmitochondriaryanodine receptorsarcoplasmic Ca2+-ATPaseventricular arrhythmias

Identifiers

PMID31653119
PMCPMC6862059
OpenAlexW2981461046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.