Evidence map›Paper›PMID 31653094›Full record

ArticleCancers2019

Tumor BRCA Test for Patients with Epithelial Ovarian Cancer: The Role of Molecular Pathology in the Era of PARP Inhibitor Therapy.

Caterina Fumagalli, Federica Tomao, Ilaria Betella, Alessandra Rappa, Mariarosaria Calvello, Bernardo Bonanni, Loris Bernard, Fedro Peccatori, Nicoletta Colombo, Giuseppe Viale and 2 more

Abstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Cost-Effectiveness Analysis of Germline and SomaticAnnals of laboratory medicine · 2023
    Article
  4. Laboratory Cross-Comparison and Ring Test Trial for TumorJournal of personalized medicine · 2022
    Article
  5. Article
  6. A commentary on the discrepancy between blood and tumour BRCA testing: An open question.BJOG : an international journal of obstetrics and gynaecology · 2022
    Article
  7. Epithelial Ovarian Cancer: Providing Evidence of Predisposition Genes.International journal of environmental research and public health · 2022
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Tumour Versus GermlineDiagnostics (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Caterina FumagalliDivision of Pathology, European Institute of Oncology (IEO), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), 20141 Milan, Italy. caterina.fumagalli@ieo.it.
Federica TomaoDepartment of Obstetric, Gynecologic and Urologic Sciences, University of Rome "Sapienza", 00161 Rome, Italy. federica.tomao@uniroma1.it.
Ilaria BetellaDivision of Gynecologic Surgery, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy. ilaria.betella@ieo.it.ORCID 0000-0001-9191-8228
Alessandra RappaDivision of Pathology, European Institute of Oncology (IEO), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), 20141 Milan, Italy. alessandra.rappa@ieo.it.
Mariarosaria CalvelloDivision of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy. mariarosaria.calvello@ieo.it.ORCID 0000-0003-2113-8503
Bernardo BonanniDivision of Cancer Prevention and Genetics, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy. bernardo.bonanni@ieo.it.
Loris BernardClinical Genomics Lab, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy. loris.bernard@ieo.it.
Fedro PeccatoriDivision of Gynecologic Oncology, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy. fedro.peccatori@ieo.it.ORCID 0000-0001-8227-8740
Nicoletta ColomboDivision of Gynecologic Oncology, IEO, European Institute of Oncology IRCCS, 20141 Milan, Italy. nicoletta.colombo@ieo.it.
Giuseppe VialeDivision of Pathology, European Institute of Oncology (IEO), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), 20141 Milan, Italy. giuseppe.viale@ieo.it.
Massimo BarberisDivision of Pathology, European Institute of Oncology (IEO), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), 20141 Milan, Italy. massimo.barberis@ieo.it.
Elena Guerini-RoccoDivision of Pathology, European Institute of Oncology (IEO), Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), 20141 Milan, Italy. elena.guerinirocco@ieo.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The PARP inhibitor olaparib has been approved in the maintenance setting of platinum-sensitive epithelial ovarian cancer patients with germline or somatic

Indexed as

BRCA1/2next-generation sequencingovarian cancer

Identifiers

PMID31653094
PMCPMC6896171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.