Evidence map›Paper›PMID 31653081›Full record

ArticleJournal of clinical medicine2019

Serum Level and Activity of Butylcholinesterase: A Biomarker for Post-Stroke Dementia.

Yi-Chun Chen, Wen-Hai Chou, Chiu-Ping Fang, Tung-Hsia Liu, Hsiao-Hui Tsou, Yun Wang, Yu-Li Liu

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Small Vessel Disease-Related Dementia: An Invalid Neurovascular Coupling?International journal of molecular sciences · 2020
    Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yi-Chun ChenDepartment of Neurology, Chang Gung Memorial Hospital Linkou Medical Center and College of Medicine, Chang Gung University, Taoyuan 333, Taiwan. ycchen.cgmh@gmail.com.
Wen-Hai ChouCenter for Neuropsychiatric Research, National Health Research Institutes, Miaoli County 35053, Taiwan. ycchen.cgmh@gmail.com.
Chiu-Ping FangCenter for Neuropsychiatric Research, National Health Research Institutes, Miaoli County 35053, Taiwan. eikon@nhri.org.tw.
Tung-Hsia LiuCenter for Neuropsychiatric Research, National Health Research Institutes, Miaoli County 35053, Taiwan. wenliu@nhri.org.tw.
Hsiao-Hui TsouDivision of Biostatistics and Bioinformatics, Institute of Population Health Sciences, National Health Research Institutes, Miaoli County 35053, Taiwan. 940903@nhri.org.tw.
Yun WangCenter for Neuropsychiatric Research, National Health Research Institutes, Miaoli County 35053, Taiwan. 020120@nhri.edu.tw.
Yu-Li LiuCenter for Neuropsychiatric Research, National Health Research Institutes, Miaoli County 35053, Taiwan. ylliou@nhri.org.tw.
National Health Research Institutes · TWChang Gung University · TW

Funding

Chang Gung Medical Foundation, Taiwan CMRPG3E1502, CMRPG3H1831, CMRPG3J0931Ministry of Science and Technology, Executive Yuan, Taiwan MOST108-2314-B-182A-047 and MOST108-2629-B-182A-005National Health Research Institutes and Central Government S & T grant, Taiwan 106-1901-01-10-02, 107-1901-01-19-02, and 108-1901-01-19-08National Health Research Institutes, Zhunan, Taiwan NP-107-SP-04 and NP-108-SP-04
6 · The paper itself

Abstract

Cholinergic neurotransmission regulates the immune response and inhibits cytokine release after stroke. The changes in the level/activity of blood cholinesterase (ChE) in patients with post-stroke dementia (PSD) are less known. This study aimed to examine post-stroke plasma acetylcholinesterase (AChE) and butylcholinesterase (BChE) and determine whether they are biomarkers for PSD. Thirty patients with PSD, 87 post-stroke patients without dementia (PSNoD), and 117 age- and gender-matched healthy controls were recruited. Missense genetic variants

Indexed as

biomarkercerebral infarctioncholinergic systemdementiapost-stroke dementiastroke

Identifiers

PMID31653081
PMCPMC6912582
OpenAlexW2981613934

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.