Evidence map›Paper›PMID 31653034›Full record

ArticleCells2019

Promising Prognosis Marker Candidates on the Status of Epithelial-Mesenchymal Transition and Glioma Stem Cells in Glioblastoma.

Yasuo Takashima, Atsushi Kawaguchi, Ryuya Yamanaka

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 44 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yasuo TakashimaLaboratory of Molecular Target Therapy for Cancer, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan. ytakashi@koto.kpu-m.ac.jp.ORCID 0000-0001-8876-6673
Atsushi KawaguchiCenter for Comprehensive Community Medicine, Faculty of Medicine, Saga University, Saga 849-8501, Japan. akawa@cc.saga-u.ac.jp.
Ryuya YamanakaLaboratory of Molecular Target Therapy for Cancer, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto 602-8566, Japan. ryaman@koto.kpu-m.ac.jp.ORCID 0000-0003-2941-7996
Kyoto Prefectural University of Medicine · JPSaga University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multivariable analyses of global expression profiling are valid indicators of the prognosis of various diseases including brain cancers. To identify the candidates for markers of prognosis of glioblastoma, we performed multivariable analyses on the status of epithelial (EPI)-mesenchymal (MES) transition (EMT), glioma (GLI) stem cells (GSCs), molecular target therapy (MTT), and potential glioma biomarkers (PGBs) using the expression data and clinical information from patients. Random forest survival and Cox proportional hazards regression analyses indicated significant variable values for

Indexed as

AdultBiomarkers, TumorDatabases, GeneticEpithelial-Mesenchymal TransitionFemaleGene ExpressionGene Expression Regulation, NeoplasticGlioblastomaGliomaHumansKaplan-Meier EstimateMaleNeoplastic Stem CellsPrognosisProportional Hazards ModelsTranscriptomeBiomarkers, Tumorepithelial-mesenchymal transitionglioblastomaglioma stem cellmultivariable analysisprognosis prediction

Identifiers

PMID31653034
PMCPMC6912254
OpenAlexW2982074880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.