Evidence map›Paper›PMID 31653005›Full record

ArticleBiomolecules2019

Design of N-Terminal Derivatives from a Novel Dermaseptin Exhibiting Broad-Spectrum Antimicrobial Activity against Isolates from Cystic Fibrosis Patients.

Yuan Ying, Hui Wang, Xinping Xi, Chengbang Ma, Yue Liu, Mei Zhou, Qiang Du, James F Burrows, Minjie Wei, Tianbao Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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  6. Evaluation of Peptide-Based Probes towardACS infectious diseases · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Yuan YingSchool of Pharmacy, China Medical University, Shenyang 110001, China. yying01@qub.ac.uk.
Hui WangSchool of Pharmacy, China Medical University, Shenyang 110001, China. hwang@cmu.edu.cn.
Xinping XiNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. x.xi@qub.ac.uk.
Chengbang MaNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. c.ma@qub.ac.uk.
Yue LiuNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. yliu58@qub.ac.uk.
Mei ZhouNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. m.zhou@qub.ac.uk.ORCID 0000-0003-2576-0252
Qiang DuSchool of Pharmacy, China Medical University, Shenyang 110001, China. qdu@cmu.edu.cn.
James F BurrowsNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. j.burrows@qub.ac.uk.
Minjie WeiSchool of Pharmacy, China Medical University, Shenyang 110001, China. mjwei@hotmail.com.
Tianbao ChenNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. t.chen@qub.ac.uk.ORCID 0000-0001-8011-9260
Lei WangNatural Drug Discovery Group, School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK. l.wang@qub.ac.uk.ORCID 0000-0002-8811-8489
Queen's University Belfast · GBChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermaseptins are an antimicrobial peptide family widely identified from the skin secretions of phyllomeudusinae frogs. Here, we identify Dermaseptin-PC (DM-PC), from the skin secretion of

Indexed as

Amino Acid SequenceAmphibian ProteinsAnimalsAnti-Infective AgentsAntimicrobial Cationic PeptidesAnuraBacteriaBiofilmsCandida albicansCystic FibrosisErythrocytesHemolysisHorsesHumansMagnesium ChlorideSkinAmphibian ProteinsAnti-Infective AgentsAntimicrobial Cationic PeptidesdermaseptinMagnesium Chlorideantimicrobial peptidecystic fibrosis infectiondermaseptinpeptide design

Identifiers

PMID31653005
PMCPMC6920804
OpenAlexW2981566651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.