Evidence map›Paper›PMID 31652985›Full record

ArticleNanomaterials (Basel, Switzerland)2019

Tuning the Properties of Nanogel Surfaces by Grafting Charged Alkylamine Brushes.

Zbyšek Posel, Paola Posocco

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zbyšek PoselDepartment of Informatics, Faculty of Science, Jan Evangelista Purkyně University in Ústí nad Labem, 40096 Ústí nad Labem, Czech Republic. zbysek.posel@ujep.cz.ORCID 0000-0003-4271-5349
Paola PosoccoDepartment of Engineering and Architecture, University of Trieste, 34127 Trieste, Italy. paola.posocco@dia.units.it.ORCID 0000-0001-8129-1572

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanogels are chemically crosslinked polymeric nanoparticles endowed with high encapsulation ability, tunable size, ease of preparation, and responsiveness to external stimuli. The presence of specific functional groups on their surfaces provides an opportunity to tune their surface properties and direct their behavior. In this work, we used mesoscale modeling to describe conformational and mechanical properties of nanogel surfaces formed by crosslinked polyethylene glycol and polyethyleneimine, and grafted by charged alkylamine brushes of different lengths. Simulations show that both number of chains per area and chain length can be used to tune the properties of the coating. Properly selecting these two parameters allows switching from a hydrated, responsive coating to a dried, highly charged layer. The results also suggest that the scaling behavior of alkylamine brushes, e.g., the transition from a mushroom to semi-dilute brush, is only weakly coupled with the shielding ability of the coating and much more with its compressibility.

Indexed as

adsorptioncharged brushesdissipative particle dynamicsnanogelsresponsive surfacessmart surfaces

Identifiers

PMID31652985
PMCPMC6915512

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.