Evidence map›Paper›PMID 31652958›Full record

ArticleMetabolites2019

Quantitative

Amanda L Fuchs, Sage M Schiller, Wyatt J Keegan, Mary Cloud B Ammons, Brian Eilers, Brian Tripet, Valérie Copié

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Review
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  13. 1,2-Current issues in molecular biology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Amanda L FuchsDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA. afuchs03143@gmail.com.
Sage M SchillerDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA. sageschiller2@gmail.com.
Wyatt J KeeganDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA. wjkeegan@msn.com.
Mary Cloud B AmmonsDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA. marycloud.ammonsanderson@va.gov.ORCID 0000-0002-9717-0844
Brian EilersDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA. bjeilers@gmail.com.
Brian TripetDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA. brian.tripet@gmail.com.
Valérie CopiéDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, MT 59717, USA. vcopie@montana.edu.ORCID 0000-0002-2778-1463
Montana State University · US

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI BRIAN P BOTHNER · 2012 to 2026
$60.0M
Metabolomic Analysis as a Tool to Understanding the Use of Novel Therapeutics in a Host-Pathogen Model of the Chronic Wound EnvironmentK01GM103821 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI AMMONS, MARY CLOUD BOSWORTH · 2012 to 2016
$490k
Understanding and Integrating the Metabolome, Microbiome, and Innate Immunity in Diabetic WoundsR03AI135998 · NIAID · IDAHO VETERANS RESEARCH / EDUCATION FDN · PI AMMONS, MARY CLOUD BOSWORTH · 2018 to 2019
$139k
Montana Research Initiative 51040-MUSRI2015-03Montana State University Vice President for Research and Economic Development OfficeMurdock Charitable Trust Foundation 2015066:MNLNational Science Foundation NSF-MRI:DBI-1532078NIAID NIH HHS R03 AI135998NIGMS NIH HHS K01 GM103821NIH HHS 1K01GM103821-04NIH HHS 1S10RR13878; 1S10RR026659NIH HHS DK R01 DK1147-01A1NIH HHS P20GM103474
6 · The paper itself

Abstract

Macrophages (MΦs) are phagocytic immune cells that are found in nearly all human tissues, where they modulate innate and adaptive immune responses, thereby maintaining cellular homeostasis. MΦs display a spectrum of functional phenotypes as a result of microenvironmental and stress-induced stimuli. Evidence has emerged demonstrating that metabolism is not only crucial for the generation of energy and biomolecular precursors, but also contributes to the function and plasticity of MΦs. Here, 1D

Indexed as

glycolysisimmunometabolismKennedy pathwaymetabolomicsNMRoxidative stressprimary human macrophagesTCA cycle

Identifiers

PMID31652958
PMCPMC6918149
OpenAlexW2981962183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.