Evidence map›Paper›PMID 31652943›Full record

ArticleInternational journal of molecular sciences2019

The CCR4-NOT Deadenylase Complex Maintains Adipocyte Identity.

Akinori Takahashi, Shohei Takaoka, Shungo Kobori, Tomokazu Yamaguchi, Sara Ferwati, Keiji Kuba, Tadashi Yamamoto, Toru Suzuki

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. TheBiomolecules · 2025
    Review
  2. PARN Maintains RNA Stability to Regulate Insulin Maturation and GSIS in Pancreatic β Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Akinori TakahashiCell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan. akinori.takahashi@oist.jp.
Shohei TakaokaCell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan. shohei.takaoka@oist.jp.
Shungo KoboriNucleic Acid Chemistry and Engineering Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan. shungo.kobori@oist.jp.
Tomokazu YamaguchiDepatment of Biochemistry and Metabolic Science, Graduate School of Medicine, Akita University, Akita 010-8543, Japan. yamaguchit@med.akita-u.ac.jp.
Sara FerwatiCell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan. Sara.Ferwati@mail.mcgill.ca.
Keiji KubaDepatment of Biochemistry and Metabolic Science, Graduate School of Medicine, Akita University, Akita 010-8543, Japan. kuba@med.akita-u.ac.jp.ORCID 0000-0002-2203-5293
Tadashi YamamotoCell Signal Unit, Okinawa Institute of Science and Technology Graduate University, Okinawa 904-0495, Japan. tadashi.yamamoto@oist.jp.
Toru SuzukiLaboratory for Immunogenetics, Center for Integrative Medical Sciences, RIKEN, Kanagawa 230-0045, Japan. toru.suzuki.ff@riken.jp.ORCID 0000-0003-1864-8027
Okinawa Institute of Science and Technology Graduate University · JPAkita University · JPRIKEN Center for Integrative Medical Sciences · JP

Funding

Japan Society for the Promotion of Science 21229006, 17K07292, 18K07079, 10J08349, 25860761, 25121734, 17H06018
6 · The paper itself

Abstract

Shortening of poly(A) tails triggers mRNA degradation; hence, mRNA deadenylation regulates many biological events. In the present study, we generated mice lacking the

Indexed as

AdipocytesAdipose Tissue, BrownAdipose Tissue, WhiteAnimalsBody TemperatureCells, CulturedGene Expression RegulationHyperglycemiaHyperinsulinismLipid MetabolismMiceMice, Inbred C57BLMice, KnockoutRNA, MessengerTranscription FactorsRNA, MessengerTranscription Factorsadipocyteccr4–not complexlipodystrophy

Identifiers

PMID31652943
PMCPMC6862216
OpenAlexW2982002069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.