Evidence map›Paper›PMID 31652902›Full record

ArticleNutrients2019

Impact of Vitamin D Deficit on the Rat Gut Microbiome.

Iñaki Robles-Vera, María Callejo, Ricardo Ramos, Juan Duarte, Francisco Perez-Vizcaino

Abstract read
In one paragraph

Article in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Iñaki Robles-VeraDepartment of Pharmacology, School of Pharmacy, Universidad de Granada, 18071 Granada, Spain. roblesverai@ugr.es.
María CallejoDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain. maria.callejo@ucm.es.
Ricardo RamosFundación Parque Científico de Madrid, 28049 Madrid, Spain. ricardo.ramos@fpcm.es.
Juan DuarteDepartment of Pharmacology, School of Pharmacy, Universidad de Granada, 18071 Granada, Spain. jmduarte@ugr.es.
Francisco Perez-VizcainoDepartment of Pharmacology and Toxicology, School of Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain. fperez@med.ucm.es.

Funding

Ministerio de Economía, Industria y Competitividad, Gobierno de España SAF2016-77222-R, SAF2017-8489-R
6 · The paper itself

Abstract

Inadequate immunologic, metabolic and cardiovascular homeostasis has been related to either an alteration of the gut microbiota or to vitamin D deficiency. We analyzed whether vitamin D deficiency alters rat gut microbiota. Male Wistar rats were fed a standard or a vitamin D-free diet for seven weeks. The microbiome composition was determined in fecal samples by 16S rRNA gene sequencing. The vitamin D-free diet produced mild changes on α- diversity but no effect on β-diversity in the global microbiome. Markers of gut dysbiosis like

Indexed as

Gastrointestinal MicrobiomeVitamin D DeficiencyAnimalsBacteriaDNA, BacterialMaleRatsRats, WistarRNA, BacterialRNA, Ribosomal, 16SVitamin D25-hydroxyvitamin DDNA, BacterialRNA, BacterialRNA, Ribosomal, 16SVitamin D16S rRNA sequencingmicrobiotavitamin D deficit

Identifiers

PMID31652902
PMCPMC6893507

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.