Evidence map›Paper›PMID 31652835›Full record

ArticleMarine drugs2019

Identification of Fromiamycalin and Halaminol A from Australian Marine Sponge Extracts with Anthelmintic Activity against

H M P Dilrukshi Herath, Sarah Preston, Abdul Jabbar, Jose Garcia-Bustos, Aya C Taki, Russell S Addison, Sasha Hayes, Karren D Beattie, Sean L McGee, Sheree D Martin and 6 more

Abstract read
In one paragraph

Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. First report ofVeterinary world · 2025
    Article
  2. Article
  3. Review
  4. Article
  5. Evaluation of Serum Supplementation on the Development ofInternational journal of molecular sciences · 2025
    Article
  6. Virtual screening, molecular dynamics simulations, andFrontiers in veterinary science · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Phytochemical characterization ofFrontiers in chemistry · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Natural Compounds from the Marine Brown AlgaPathogens (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

H M P Dilrukshi HerathFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia. herathh@student.unimelb.edu.au.
Sarah PrestonFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia. sjpreston@federation.edu.au.
Abdul JabbarFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia. jabbara@unimelb.edu.au.
Jose Garcia-BustosFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia. Jose.GarciaB@unimelb.edu.au.
Aya C TakiFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia. aya.taki@unimelb.edu.au.
Russell S AddisonGriffith Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. bchang@yourgene.com.tw.
Sasha HayesGriffith Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. sasha.hayes@griffith.edu.au.
Karren D BeattieGriffith Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. sjpreston@federation.edu.au.
Sean L McGeeMetabolic Research Unit, Metabolic Reprogramming Laboratory, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria 3216, Australia. r.addison@griffith.edu.au.
Sheree D MartinMetabolic Research Unit, Metabolic Reprogramming Laboratory, School of Medicine, Faculty of Health, Deakin University, Waurn Ponds, Victoria 3216, Australia. sasha.hayes@griffith.edu.au.
Merrick G EkinsQueensland Museum, South Brisbane BC, QLD 4101, Australia. k.beattie@griffith.edu.au.
John N A HooperQueensland Museum, South Brisbane BC, QLD 4101, Australia. sean.mcgee@deakin.edu.au.
Bill C H ChangFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia. sheree.martin@deakin.edu.au.
Andreas HofmannFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia. a.hofmann@structuralchemistry.org.
Rohan A DavisGriffith Institute for Drug Discovery, Griffith University, Brisbane, QLD 4111, Australia. robinbg@unimelb.edu.au.
Robin B GasserFaculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia. r.davis@griffith.edu.au.

Funding

Australian Research Council #1The University of Melbourne #3Yourgene Health #2
6 · The paper itself

Abstract

There is an urgent need to discover and develop new anthelmintics for the treatment of parasitic nematodes of veterinary importance to circumvent challenges linked to drug resistant parasites. Being one of the most diverse natural ecosystems, the marine environment represents a rich resource of novel chemical entities. This study investigated 2000 extracts from marine invertebrates, collected from Australian waters, for anthelmintic activity. Using a well-established in vitro bioassay, these extracts were screened for nematocidal activity against

Indexed as

AlkaloidsAnimalsAnthelminticsAustraliaCarcinoma, HepatocellularCell Line, TumorHaemonchusLarvaPoriferaRatsAlkaloidsAnthelminticsalkaloidanthelminticfromiamycalinHaemonchus contortushalaminol AHaliclona sp.marineMonanchora unguiculata

Identifiers

PMID31652835
PMCPMC6891614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.