Evidence map›Paper›PMID 31652561›Full record

Trial reportNutrients2019

Plasma Kinetics of Choline and Choline Metabolites After A Single Dose of Superba

Yvonne Mödinger, Christiane Schön, Manfred Wilhelm, Petter-Arnt Hals

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

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  17. Cross Talk between α7 and α3β4 Nicotinic Receptors Prevents Their Desensitization in Human Chromaffin Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Yvonne MödingerBioTeSys GmbH, Schelztorstraße 54-56, 73728 Esslingen, Germany. y.moedinger@biotesys.de.
Christiane SchönBioTeSys GmbH, Schelztorstraße 54-56, 73728 Esslingen, Germany. c.schoen@biotesys.de.ORCID 0000-0003-3787-5268
Manfred WilhelmDepartment of Mathematics, Natural and Economic Sciences, Ulm University of Applied Sciences, Albert-Einstein-Allee 55, 89081 Ulm, Germany. manfred.wilhelm@thu.de.ORCID 0000-0003-1740-467X
Petter-Arnt HalsAker BioMarine Antarctic AS, Oksenøyveien 10, 1327 Lysaker, Norway. petter-arnt.hals@akerbiomarine.com.ORCID 0000-0003-4542-1290
BioTeSys (Germany) · DEBioMar (Norway) · NOTechnische Hochschule Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As an essential nutrient, the organic water-soluble compound choline is important for human health. Choline is required for numerous biological processes, including the synthesis of neurotransmitters, and it is an important prerequisite for structural integrity and the functioning of cells. A choline-rich diet provides crucial choline sources, yet additional choline dietary supplements might be needed to fully meet the body's requirements. Dependent on the structure of choline in different sources, absorption and metabolism may differ and strongly impact the bioavailability of circulating choline. This study in healthy volunteers aimed to compare the pharmacokinetics of free choline and of selected choline metabolites between the single dose intake of phosphatidylcholine, present in Superba

Indexed as

AdolescentAdultAgedAnimalsBiological ProductsCholineCross-Over StudiesEuphausiaceaFemaleFish OilsHumansKineticsMaleMiddle AgedPhosphatidylcholinesYoung AdultBiological ProductsCholineFish OilsPhosphatidylcholinesAntarctic krillbetainecholinecholine bitartratedimethylglycinepharmacokineticsphosphatidylcholineSuperbaBoosttrimethylamine N-oxide

Identifiers

PMID31652561
PMCPMC6835836
OpenAlexW2982270072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.