Evidence map›Paper›PMID 31651834›Full record

ArticleMedicine2019

Comparison of prognostic ability of perioperative myocardial biomarkers in acute type A aortic dissection.

Ming Gong, Zining Wu, Xinliang Guan, Wenjian Jiang, Hongjia Zhang

Abstract readComparative Study
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. The diagnostic value of tenascin-C in acute aortic syndrome.Journal of geriatric cardiology : JGC · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ming GongDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University.
Zining WuDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University.
Xinliang GuanDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University.
Wenjian JiangDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University.
Hongjia ZhangDepartment of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stanford type A aortic dissection (AD) is a lethal disease requiring surgery. Evidence regarding the prognostic ability of perioperative myocardiac markers on long-term outcome is limited.In this cohort study, we measured perioperative myocardiac markers level in 583 surgical patients with type A AD in our hospital between 2015 and 2017. All patients were followed up after surgery for a median period of 864 days to determine short- and long-term mortality.About one-fifth of patients has a positive preoperative myocardial markers, which was increased significantly after operation. Increase log10 post-creatine kinase MB isoenzyme (CK-MB) (hazard ratio [HR], 4.64; 95% confidence interval [CI] 1.89-11.43; P = .0008), log10 post-TnI (HR, 3.11; 95% CI 1.56-6.21; P = .0013), log10 post-Mb (HR, 3.00; 95% CI 1.40-6.43; P = .0048), log10 pre-CK-MB (HR,1.82; 95% CI 1.03-3.21; P = .0377), and upper tertile of post-CK-MB (HR,1.52; 95% CI 1.05-2.20; P = .0261) were the independent risk factor for 30 days mortality adjusted for potential confounders. None of cardiac markers was significantly associated with long-term outcome independent of other factors.Perioperative myocardiac predicts early outcome in type A AD patients undergoing surgery. Increasing perioperative myocardial markers do not appear to be a predictor for long-term all-cause mortality.

Indexed as

AdultAortic DissectionBiomarkersCreatine Kinase, MB FormFemaleHumansMaleMiddle AgedPostoperative PeriodPredictive Value of TestsPreoperative PeriodPrognosisProportional Hazards ModelsRetrospective StudiesRisk FactorsTreatment OutcomeBiomarkersCreatine Kinase, MB FormTroponin I

Identifiers

PMID31651834
PMCPMC6824686

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.