ArticleBMC pediatrics2019
Prevalence and associated factors of neurodevelopmental disability among infants in eastern Uganda: a population based study.
Article in BMC pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- The association of breastfeeding with cognitive development and educational achievement in sub-Saharan Africa: A systematic review.Journal of global health · 2022Pooled it
- Trial
- Effect of probable neonatal sepsis on the development of infants in Eastern Uganda (ENON): a cohort study.BMJ paediatrics open · 2026Article
- "You don't expect a miracle to happen soon": a qualitative study of psychosocial support needs of caregivers of children with disability in Eastern Uganda.BMC pediatrics · 2026Article
- Screening young children for neurodevelopmental differences in sub-Saharan Africa: a scoping review.BMC psychiatry · 2025Article
- Neurodevelopmental problems in pre-school children in rural Western Cape, South Africa: is community screening feasible?BMC psychiatry · 2025Article
- Predictors of neurodevelopment outcomes among children under 5 years old in Nairobi informal settlements.Frontiers in neuroscience · 2025Article
- Article
- Identifying and quantifying initial post-discharge needs for clinical review of sick, newborns in Kenya based on a large multi-site, retrospective cohort study.Frontiers in pediatrics · 2024Article
- Alopecia areata-like pattern of baldness: the most recent update and the expansion of novel phenotype and genotype in the CTNNB1 gene.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Neurodevelopmental Outcome at 6 Months Following Neonatal Resuscitation in Rural Tanzania.Children (Basel, Switzerland) · 2023Article
- Diagnostic accuracy of ASQ for screening of neurodevelopmental delays in low resource countries.BMJ open · 2023Article
- Effects of short-term quarantine on growth and development of children aged 1-36 months during the Omicron outbreak.European journal of pediatrics · 2023Article
- High Burden of Neurodevelopmental Delay among Children Born to Women with Obstructed Labour in Eastern Uganda: A Cohort Study.International journal of environmental research and public health · 2023Article
- Association of perinatal factors with suspected developmental delay in urban children aged 1-36 months - a large-scale cross-sectional study in China.BMC pediatrics · 2023Article
- Comparative study of the relationship between pregnancy and childbirth factors and autism in healthy children and children with autism.Journal of education and health promotion · 2023Article
- Factors associated with birth asphyxia among term singleton births at two referral hospitals in Northern Uganda: a cross sectional study.BMC pregnancy and childbirth · 2022Article
- Health facility readiness to care for high risk newborn babies for early childhood development in eastern Uganda.BMC health services research · 2022Article
- Neurodevelopmental outcomes of preterm babies during infancy in Eastern Uganda: a prospective cohort study.Global health action · 2020Article
- Caring for children with neurodevelopmental disability: Experiences from caretakers and health workers in rural eastern Uganda.PloS one · 2020Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeurodevelopmental disability (NDD) is increasingly acknowledged as one of the important causes of disease burden in low income countries. None the less, there is a dearth of data on the burden of NDD and its determinants in these settings. We aimed to establish the prevalence and factors associated with NDD among infants in Eastern Uganda.
methodsWe assessed 487 infants aged 9-12 months within Iganga-Mayuge Health Demographic Surveillance Site in Eastern Uganda using the Malawi Developmental Assessment Tool. The tool has four domains: gross motor, fine motor, language and social domains. An infant failed a domain if she/he failed more than two parameters of the expected at his/her age. We interviewed mothers on factors that could influence the infants' neurodevelopmental outcomes. Data were analysed using STATA version 14. We used odds ratios and 95% confidence intervals to assess statistical significance of associations.
resultsOf the 487 infants, 62(12.7%) had an NDD in at least one of the domains. The most affected was social behaviour where 52(10.7%) infants had an NDD. Severe impairment was seen among 9(1.8%) infants with NDD in either three or four domains. Factors associated with NDD at multivariate logistic regression included: parity of more than three children (aOR = 1.8, 95% CI: 1.02-3.18); failure to cry at birth (aOR = 3.6, 95% CI: 1.46-9.17) and post-neonatal complications (aOR = 4.15, 95% CI: 1.22-14.10). Low birth weight, immediate and exclusive breast feeding were not significantly associated with NDD.
conclusionWe found a high NDD burden among infants particularly in the social behaviour domain. To optimise the socio-neural development of infants, programs are needed to educate and work with families on how to engage and stimulate infants. Existing immunisation clinics and community health worker strategies provide an excellent opportunity for stemming this burden.
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