Evidence map›Paper›PMID 31650987›Full record

ArticleCanada communicable disease report = Releve des maladies transmissibles au Canada2019

Surveillance of laboratory exposures to human pathogens and toxins: Canada 2018.

D Choucrallah, L Sarmiento, S Ettles, F Tanguay, M Heisz, E Falardeau

Open access · diamondAbstract read
In one paragraph

Article in Canada communicable disease report = Releve des maladies transmissibles au Canada, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Surveillance of laboratory exposures to human pathogens and toxins, Canada, 2024.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  2. Surveillance of laboratory exposures to human pathogens and toxins, Canada, 2023.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  3. Canadian laboratory incidents with human pathogens and toxins: An overview of reports, 2016-2022.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2024
    Article
  4. Article
  5. Surveillance of laboratory exposures to human pathogens and toxins, Canada, 2021.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  6. Multivariate analyses of risk factors associated with laboratory exposure incidents.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  7. Laboratory-acquired infections in Canada from 2016 to 2021.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2022
    Article
  8. Review
  9. Surveillance of laboratory exposures to human pathogens and toxins, Canada 2020.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

D ChoucrallahPublic Health Agency of Canada, Centre for Biosecurity, Ottawa, ON.
L SarmientoPublic Health Agency of Canada, Centre for Biosecurity, Ottawa, ON.
S EttlesPublic Health Agency of Canada, Centre for Biosecurity, Ottawa, ON.
F TanguayPublic Health Agency of Canada, Centre for Biosecurity, Ottawa, ON.
M HeiszPublic Health Agency of Canada, Centre for Biosecurity, Ottawa, ON.
E FalardeauPublic Health Agency of Canada, Centre for Biosecurity, Ottawa, ON.
Public Health Agency of Canada · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Laboratory Incident Notification Canada (LINC) surveillance system monitors laboratory incidents reported under the

objectiveTo describe the laboratory exposure and laboratory-acquired infection incidents that occurred in Canada in 2018 compared to previous years, and then by sector, human pathogens and toxins involved, number of affected persons, incident type and root causes.

methodsLaboratory incidents that occurred in 2018 were reported through the LINC system. The number of laboratory incidents, people exposed and laboratory-acquired infections were compared to previous years, then the incidents were analyzed by sector, human pathogen or toxin involved, the type of incident, people exposed, route of exposure and root causes. Microsoft Excel 2016 was used for descriptive analysis.

resultsIn 2018, there were 89 exposure incidents to human pathogens and 235 people were exposed. There were five suspected and one confirmed laboratory-acquired infections. This was approximately twice the number of exposure incidents that were reported in 2017 (n=44) and 2016 (n=46). The highest number of exposure incidents occurred in the academic and hospital sectors, and the ratio of incidence to licences was the lowest in the private sector. The majority of incidents (n=50; 56%) involved Risk Group 2 human pathogens that were manipulated in a Containment Level 2 laboratory. Most exposures were related to sharps or procedures and the most common people exposed were laboratory technicians. Human interaction and standard operating procedures were the leading root causes.

conclusionAlthough overall the annual incidence of laboratory exposures in Canada remains relatively low, the incidence was higher in 2018 than in previous years. Whether this is a true increase in incidence or an increase in reporting is not known at this time as baseline estimates are still being established.

Indexed as

Centre for Biosecurityhuman pathogens and toxinslaboratory-acquired infectionslaboratory exposuresLaboratory Incident Notification Canadalaboratory incidentssurveillance

Identifiers

PMID31650987
PMCPMC6781952
OpenAlexW2971517797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.