Evidence map›Paper›PMID 31650968›Full record

ArticleDiagnostic and interventional radiology (Ankara, Turkey)2019

Hyperintensity at fat spared area in steatotic liver on the hepatobiliary phase MRI.

Emre Ünal, İlkay Sedakat İdilman, Ali Devrim Karaosmanoğlu, Mustafa Nasuh Özmen, Deniz Akata, Muşturay Karcaaltıncaba

Abstract readComparative Study
In one paragraph

Article in Diagnostic and interventional radiology (Ankara, Turkey), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Emre ÜnalDepartment of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.
İlkay Sedakat İdilmanDepartment of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.
Ali Devrim KaraosmanoğluDepartment of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.
Mustafa Nasuh ÖzmenDepartment of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.
Deniz AkataDepartment of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.
Muşturay KarcaaltıncabaDepartment of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to investigate the reasons for hyperintensity at fat spared area in steatotic liver at hepatobiliary phase (HBP) on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) enhanced liver magnetic resonance imaging.

methodsTwenty-two patients with focal fat spared area demonstrating hyperintensity on HBP images were included. A region of interest was placed on in- and opposed-phase images at fat spared area and liver to measure the fat. The measurement was also performed on precontrast T1-weighted and HBP images. The signal intensities of spleen, kidney, muscle, intervertebral disc, and spinal cord were also recorded.

resultsThe mean fat fraction of liver and fat spared area was 24.86% (8%-46%) and 8.41% (1%-34%), respectively (P < 0.001). There was a significant positive correlation between liver parenchyma fat fraction and delta fat fraction (r=0.74, P < 0.001). The mean signal intensity values of fat spared areas were higher compared with liver on precontrast T1-weighted and HBP images (P < 0.001). The mean relative enhancement ratio of liver and fat spared areas were 0.98 (0.05-1.90) and 1.15 (0.22-2.03), respectively (P < 0.001). However, in 6 patients, the relative enhancement ratio of liver and fat spared areas were almost equal. The uptake of Gd-EOB at fat spared area was not correlated with the degree of steatosis (r = -0.01, P = 0.95).

conclusionFat spared area in steatotic liver appears hyperintense on HBP images due to increased relative enhancement ratio and/or baseline hyperintensity on precontrast images.

Indexed as

Adipose TissueAdiposityAdministration, IntravenousAdultAgedContrast MediaFatty LiverFemaleGadolinium DTPAHumansImage EnhancementImaging, Three-DimensionalLiverMagnetic Resonance ImagingMaleMiddle AgedContrast MediaGadolinium DTPAgadolinium ethoxybenzyl DTPA

Identifiers

PMID31650968
PMCPMC6837304

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