Evidence map›Paper›PMID 31650500›Full record

Trial reportCanadian journal of anaesthesia = Journal canadien d'anesthesie2020

Evaluation of hyperoxia-induced hypercapnia in obese patients after cardiac surgery: a randomized crossover comparison of conservative and liberal oxygen administration.

Marie-Hélène Denault, Carolanne Ruel, Mathieu Simon, Pierre-Alexandre Bouchard, Serge Simard, François Lellouche

Registry-linked trialOpen access · bronzeAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02917668 (Evaluation of the Risk of Hyperoxia-induced Hypercapnia in Obese Patients in a Cardiac Surgery Postoperative Setting), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02917668 nacompletednot on this map

Evaluation of the Risk of Hyperoxia-induced Hypercapnia in Obese Patients in a Cardiac Surgery Postoperative Setting

TypeinterventionalSponsorLaval UniversityRan2016 to 2018Enrolled30ConditionsObesity, Hyperoxia, HypercapniaArmsFreeO2, Usual care
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marie-Hélène DenaultInstitut universitaire de cardiologie et de pneumologie de Québec - Université Laval Research Center, 2725 Chemin Ste-Foy, Quebec, QC, G1V 4G5, Canada. marie-helene.denault.1@ulaval.ca.ORCID http://orcid.org/0000-0002-8210-6364
Carolanne RuelInstitut universitaire de cardiologie et de pneumologie de Québec - Université Laval Research Center, 2725 Chemin Ste-Foy, Quebec, QC, G1V 4G5, Canada.
Mathieu SimonInstitut universitaire de cardiologie et de pneumologie de Québec - Université Laval Research Center, 2725 Chemin Ste-Foy, Quebec, QC, G1V 4G5, Canada.
Pierre-Alexandre BouchardInstitut universitaire de cardiologie et de pneumologie de Québec - Université Laval Research Center, 2725 Chemin Ste-Foy, Quebec, QC, G1V 4G5, Canada.
Serge SimardInstitut universitaire de cardiologie et de pneumologie de Québec - Université Laval Research Center, 2725 Chemin Ste-Foy, Quebec, QC, G1V 4G5, Canada.
François LelloucheInstitut universitaire de cardiologie et de pneumologie de Québec - Université Laval Research Center, 2725 Chemin Ste-Foy, Quebec, QC, G1V 4G5, Canada.
Institut universitaire de cardiologie et de pneumologie de Québec · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecent studies on patients with stable obesity-hypoventilation syndrome have raised concerns about hyperoxia-induced hypercapnia in this population. This study aimed to evaluate whether a higher oxygen saturation target would increase arterial partial pressure of carbon dioxide (PaCO

methodsObese patients having CABG were recruited. With a randomized crossover design, we compared two oxygenation strategies for 30 min each, immediately after extubation: a peripheral oxygen saturation (SpO

resultsThirty patients were included. Mean (standard deviation [SD]) body mass index (BMI) was 34 (3) kg·m

conclusionThis study did not show a clinically important increase in PaCO

trial registrationwww.clinicaltrials.gov (NCT02917668); registered 25 September, 2016.

Indexed as

Cardiac Surgical ProceduresHypercapniaHyperoxiaObesityOxygen Inhalation TherapyCarbon DioxideCross-Over StudiesHumansOxygenCarbon DioxideOxygen

Identifiers

PMID31650500
OpenAlexW2981911752

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.