ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2020
Opioid Craving in Human Laboratory Settings: a Review of the Challenges and Limitations.
Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Cocaine craving and use during pharmacotherapy trials for cocaine use disorder: A multi-trajectory analysis.Drug and alcohol dependence · 2025Trial
- Effectiveness of Attentional Bias Modification Combined With Cognitive Behavioral Therapy in Reducing Relapse Risk and Cravings in Male Patients With Alcohol Use Disorder: A Quasi-Randomized Controlled Trial.Neuropsychopharmacology reports · 2025Trial
- Perceived stress and severity of male etomidate use disorder in China: a moderated mediation model of anxiety symptoms severity and emotion regulation difficulties.Frontiers in psychology · 2026Article
- Reliability and clinical utility of heroin craving questionnaire factors in treatment-enrolled individuals with opioid use disorder.Drug and alcohol dependence · 2025Article
- Treating Opioid Use Disorder and Opioid Withdrawal in the Context of Fentanyl.Annual review of clinical psychology · 2025Review
- Oxytocin Reduces Noradrenergic-Induced Opioid-Like Withdrawal Symptoms in Individuals on Opioid Agonist Therapy.Biological psychiatry global open science · 2025Article
- Trajectories of craving in the course of pharmacotherapy trials for methamphetamine use disorder.Addiction (Abingdon, England) · 2024Article
- Human laboratory models of reward in substance use disorder.Pharmacology, biochemistry, and behavior · 2024Review
- Patients' perspectives on buprenorphine subcutaneous implant: a case series.Journal of medical case reports · 2024Article
- Opioid use disorder (OUD) and treatment for opioid problems among OUD symptom subtypes in individuals misusing opioids.Drug and alcohol dependence reports · 2024Article
- Logical fallacies and misinterpretations that hinder progress in translational addiction neuroscience.Journal of the experimental analysis of behavior · 2022Article
- A preliminary examination of the multiple dimensions of opioid craving.Drug and alcohol dependence · 2021Article
- Insights into the Neurobiology of Craving in Opioid Use Disorder.Current anesthesiology reports · 2020Article
Corrections and comments
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Authors and funding
2 authors.
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Abstract
There are many factors that need to be taken into consideration when measuring craving in a human laboratory study. This review summarizes and discusses some of the major challenges researchers are faced with when assessing opioid craving in clinical research. First, there are wide range of available assessments that have been developed for measuring craving and depending on the research questions or the underlying constructs targeted, some may be more appropriate than others. In addition to establishing the methodological point of departure for designing a study with craving, there are also different participant conditions and characteristics that need to be evaluated when selecting among the large selection of assessments available. Participant conditions/characteristics can influence the degree or frequency of opioid craving experienced. Lastly, there can be contextual conditions that affect opioid cravings such as a stressful environment that may alter cue saliency. It is recommended that researchers carefully consider the different constituents that contribute to opioid craving and to ensure a comprehensive evaluation when assessing each participant. A more thorough consideration of these challenges can help us to understand the optimal ways to measure one important and complex component of addiction.
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Registered trials
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