ArticleBiomechanics and modeling in mechanobiology2020
Stress analysis in a bone fracture fixed with topology-optimised plates.
Article in Biomechanics and modeling in mechanobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.
- Dynamic Fracture Fixation Plates: A Systematic Review of Evolving Design Approaches.Annals of biomedical engineering · 2025Pooled it
- A systematic review and meta-analyses on animal models used in bone adhesive research.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022Pooled it
- Material and Topology Optimization of Composite Bone Plate to Reduce the Stress Shielding Effect.Materials (Basel, Switzerland) · 2026Article
- Flexure-Based Locking Plates Can Modulate Interfragmentary Motion in Distal Femur and Diaphyseal Fractures: A Parametric Finite Element Analysis.Journal of biomechanical engineering · 2026Article
- Biomechanical Characterization of Metacarpal Fixation: Internal Load Determination and Evaluation of a Novel Adhesive Osteosynthesis.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Design of internal fixation implants for fracture: A review.Journal of orthopaedic translation · 2025Review
- Biomechanical evaluation of a newly designed locking plate for opening wedge high tibial osteotomy: stress distribution and stability in the presence of lateral hinge fracture.Journal of orthopaedic surgery and research · 2024Article
- Biodegradable Zn-2Cu-0.5Zr alloy promotes the bone repair of senile osteoporotic fractures via the immune-modulation of macrophages.Bioactive materials · 2024Article
- Investigation of Tensile Properties of Different Infill Pattern Structures of 3D-Printed PLA Polymers: Analysis and Validation Using Finite Element Analysis in ANSYS.Materials (Basel, Switzerland) · 2022Article
- Intercalary reconstruction of long bones by massive allograft: Comparison of construct stability ensured by three different host-graft junctions and two types of fixations in a synthetic femur model.Frontiers in pediatrics · 2022Article
- Finite element analysis of different fixation methods of screws on absorbable plate for rib fractures.Frontiers in bioengineering and biotechnology · 2022Article
- Topology Optimisation for Compliant Hip Implant Design and Reduced Strain Shielding.Materials (Basel, Switzerland) · 2021Article
- The advances of topology optimization techniques in orthopedic implants: A review.Medical & biological engineering & computing · 2021Review
- Article
- 3D Topology Optimization and Mesh Dependency for Redesigning Locking Compression Plates Aiming to Reduce Stress Shielding.International journal of bioprinting · 2021Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The design of commercially available fixation plates and the materials used for their fabrication lead to the plates being stiffer than bone. Consequently, commercial plates are prone to induce bone stress shielding. In this study, three-dimensional fixation plates are designed using topology optimisation aiming to reduce the risk of bone stress shielding. Fixation plate designs were optimised by minimising the strain energy for three levels of volume reduction (i.e. 25%, 45% and 75%). To evaluate stress shielding, changes in bone stress due to the different fixation plate designs were determined on the fracture plane of an idealised shaft of a long bone under a four-point bending load considering the effect of a patient walking with crutches of a transverse fractured tibia. Topology optimisation is a viable approach to design less stiff plates with adequate mechanical strength considering high volume reductions, which consequently increased the stress transferred to the bone fracture plane minimising bone stress shielding.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.