Evidence map›Paper›PMID 31650365›Full record

ArticleEJNMMI physics2019

Performance evaluation of Cerenkov luminescence imaging: a comparison of

J Olde Heuvel, B J de Wit-van der Veen, K N Vyas, D S Tuch, M R Grootendorst, M P M Stokkel, C H Slump

Open access · goldAbstract read
In one paragraph

Article in EJNMMI physics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Current clinical applications of Cerenkov luminescence for intraoperative molecular imaging.European journal of nuclear medicine and molecular imaging · 2024
    Review
  4. Article
  5. Review
  6. Detection of Shortwave-Infrared Cerenkov Luminescence from Medical Isotopes.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  7. Observational
  8. Review
  9. Article
  10. Intraoperative [EJNMMI research · 2021
    Article
  11. Article
  12. IntraoperativeJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2020
    Article
  13. European journal of nuclear medicine and molecular imaging · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

J Olde HeuvelDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands. j.olde.heuvel@nki.nl.
B J de Wit-van der VeenDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.
K N VyasLightpoint Medical Ltd, Misbourne Works, Waterside, Chesham, HP5 1PE, UK.
D S TuchLightpoint Medical Ltd, Misbourne Works, Waterside, Chesham, HP5 1PE, UK.
M R GrootendorstLightpoint Medical Ltd, Misbourne Works, Waterside, Chesham, HP5 1PE, UK.
M P M StokkelDepartment of Nuclear Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands.
C H SlumpRobotics and Mechatronics , Technical Medical Centre, University of Twente, Enschede, The Netherlands.
Lightpoint Medical (United Kingdom) · GBThe Netherlands Cancer Institute · NLUniversity of Twente · NL

Funding

KWF Kankerbestrijding 15175
6 · The paper itself

Abstract

backgroundCerenkov Luminescence Imaging (CLI) is an emerging technology for intraoperative margin assessment. Previous research only evaluated radionuclide 18-Fluorine (

resultsThe linearity of the system, detection limit, spatial resolution, and uniformity were determined with the LightPath imaging system. All experiments were conducted with clinically relevant activity levels in vitro, using dedicated phantoms. For both radionuclides, a linear relationship between the activity concentration and detected light yield was observed (R

conclusion

Indexed as

Cerenkov luminescence imagingGa-68 PSMAIntraoperative imagingPerformance evaluation

Identifiers

PMID31650365
PMCPMC6813407
OpenAlexW2912096945

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.