ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020
Use of gabapentinoid medications among US adults with cancer, 2005-2015.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- The 2016 CDC Opioid Guideline and Analgesic Prescribing Patterns in Older Adults With Cancer.JAMA network open · 2025Article
- Integrated gut microbiota and metabolomics analysis reveals the antitumor effects of ergosta-4,6,8(14),22-tetraen-3-one purified from the medicinal fungus pholiota adiposa in tumor-bearing mice.Frontiers in pharmacology · 2025Article
- Tramadol use in U.S. Adults With Commercial Health Insurance, 2005-2021.American journal of preventive medicine · 2024Article
- Concurrent prescribing of opioids with other sedating medications after cancer diagnosis: a population-level analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Temporal Trends in Opioid Prescribing Patterns Among Oncologists in the Medicare Population.Journal of the National Cancer Institute · 2021Article
- Current Evidence on Abuse and Misuse of Gabapentinoids.Drug safety · 2020Review
- Patient-reported outcomes collected in ambulatory oncology practices: Feasibility, patterns, and correlates.Health services research · 2020Observational
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundGabapentinoid use for long-term cancer pain control may be problematic, given unclear mechanisms of action and increased concerns for physical dependence. The purpose of this report is to examine trends of gabapentinoid use among US adults with cancer from 2005 to 2015.
methodsWe conducted a serial, cross-sectional study using data from the Medical Expenditure Panel Survey (MEPS). We performed multiple logistic regression to examine the annual percentages of gabapentinoid users, which were adjusted for age, sex, and US region of residence. The amount of gabapentinoid prescriptions filled in 2015 was also estimated.
resultsThe adjusted percentage of gabapentinoid users in 2015 was 5.60% (3.79%, 7.41%), 2.39 times greater than the percentage in 2005 (p < .001). By 2015, the number of gabapentinoid prescriptions had grown to approximately 3.52 million (2.40 million, 4.65 million).
conclusionWe observed greater than a twofold increase in the trend of gabapentinoid medication use among US adults with cancer. Investigations on the long-term efficacy of gabapentinoids for complex pain syndromes, and mitigation of risks, is essential to guide informed clinical management and keep patients safe.
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