Evidence map›Paper›PMID 31650272›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2019

Analysis of corneal stromal roughness after iFS 150 kHz and LenSx femtosecond LASIK flap creation in porcine eyes.

Juan Gros-Otero, Samira Ketabi, Rafael Cañones-Zafra, Montserrat Garcia-Gonzalez, Alberto Parafita-Fernandez, Cesar Villa-Collar, Santiago Casado, Miguel Teus

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Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Juan Gros-OteroClínica Rementería, Calle Almagro, 36, 28010, Madrid, Spain. juangros@gmail.com.ORCID http://orcid.org/0000-0002-6410-8235
Samira KetabiHospital Universitario Príncipe de Asturias, Madrid, Spain.
Rafael Cañones-ZafraHospital Universitario Príncipe de Asturias, Madrid, Spain.
Montserrat Garcia-GonzalezClínica Rementería, Calle Almagro, 36, 28010, Madrid, Spain.
Alberto Parafita-FernandezHospital Provincial de Pontevedra, Galicia, Spain.
Cesar Villa-CollarUniversidad Europea de Madrid, Madrid, Spain.
Santiago CasadoFacultad de Ciencia e Ingeniería de Alimentos, Universidad Técnica de Ambato, Ambato, Ecuador.
Miguel TeusHospital Universitario Príncipe de Asturias, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe and compare the stromal bed roughness obtained after laser in situ keratomileusis (LASIK) flap creation using a corneal femtosecond laser platform (iFS 150) and a "dual" femtosecond (FS) laser platform (LenSx).

methodsThis ex vivo experimental study was conducted in an animal model using 12 freshly enucleated porcine eyes, six with each femtosecond laser. The standard laser treatment parameters were used for the experiment. After LASIK flap creation, the corneal stromal roughness was assessed using atomic force microscopy (AFM) in contact mode immersed in liquid. In each sample, surface measurements were obtained in 60 regions of six eyes per FS laser in 10 20 × 20-micron areas of the central corneal stroma at 512 × 512-point resolution. The surface roughness was measured and the root-mean-square (RMS) values of the roughness were obtained.

resultsThe mean RMS ± standard deviation values were 430 ± 150 nm for the corneal femtosecond laser platform and 370 ± 100 nm for the dual FS laser platform (P < 0.011).

conclusionsIn this experimental study with AFM, we found smoother stromal beds after LASIK flap creation with LenSx compared to iFS 150 kHz. Further studies are needed to understand visual implications of the differences found.

Indexed as

Surgical FlapsVisual AcuityAnimalsCorneal StromaDisease Models, AnimalKeratomileusis, Laser In SituLasers, ExcimerMicroscopy, Atomic ForceMyopiaPostoperative PeriodSwineAtomic force microscopyCorneal stromal roughnessFemtosecond laserLASIK

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.