Evidence map›Paper›PMID 31650217›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2020

Yan Li, Benedikt Schaarschmidt, Lale Umutlu, Michael Forsting, Aydin Demircioglu, Anna Katharina Koch, Ole Martin, Ken Herrmann, Hendrik Juette, Andrea Tannapfel and 1 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03781284 (Positron Emission Tomography With 18F-fluorodeoxyglucose Combined With MRI for Monitoring Inflammatory Activity in Patients With Ulcerative Colitis), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03781284 nacompletednot on this map

Positron Emission Tomography With 18F-fluorodeoxyglucose Combined With MRI for Monitoring Inflammatory Activity in Patients With Ulcerative Colitis

TypeinterventionalSponsorUniversität Duisburg-EssenRan2016 to 2018Enrolled53ConditionsUlcerative ColitisArms[18F]-FDG PET/MRI, Colonoscopy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Comparison ofThe British journal of radiology · 2020
    Trial
  2. Article
  3. Review
  4. Review
  5. BMC cancer · 2021
    Article
  6. Re:European journal of nuclear medicine and molecular imaging · 2020
    Article
  7. Diagnostic Performance of Simultaneous [Journal of clinical medicine · 2020
    Article
4 · The record

Corrections and comments

  • Commented on by
    Re:2020
5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Yan LiDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany. yan.li@uk-essen.de.ORCID 0000-0002-3906-9481
Benedikt SchaarschmidtDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.
Lale UmutluDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.
Michael ForstingDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.
Aydin DemirciogluDepartment of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.
Anna Katharina KochDepartment of Internal and Integrative Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, Am Deimelsberg 34a, 45276, Essen, Germany.
Ole MartinDepartment of Diagnostic and Interventional Radiology, University Hospital Dusseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.
Ken HerrmannDepartment of Nuclear Medicine, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45147, Essen, Germany.
Hendrik JuetteDepartment of Pathology, Ruhr-Universität Hospital Bochum, Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany.
Andrea TannapfelDepartment of Pathology, Ruhr-Universität Hospital Bochum, Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany.
Jost LanghorstDepartment of Internal and Integrative Medicine, Kliniken Essen-Mitte, University of Duisburg-Essen, Am Deimelsberg 34a, 45276, Essen, Germany.
University of Duisburg-Essen · DEKliniken Essen-Mitte · DEDüsseldorf University Hospital · DEEssen University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the diagnostic performance of PET-MR enterography in detecting histological active inflammation in patients with ulcerative colitis and the impact of bowel purgation on diagnostic accuracies of PET-MR parameters.

methodsFifty patients were enrolled in this randomized controlled trial (clinicaltrials.gov [NCT03781284]). Forty patients were randomized in two study arms, in which bowel purgation was performed either before or after PET-MR enterography. All patients underwent ileocolonoscopy with mucosal biopsies after PET-MR within 24 h. Diagnostic performance of MR morphological parameters (MRmorph), diffusion-weighted imaging (DWI), and PET in detecting histological inflammation determined by the Nancy index was compared with each other and between study arms. Correlation between PET and histological inflammatory severity was calculated.

resultsIn study arm without previous bowel purgation, SUV

conclusionPET-MR enterography was an excellent non-invasive diagnostic method in the assessment of histological active inflammation in ulcerative colitis without the need of previous bowel purgation.

trial registrationhttps://clinicaltrials.gov/ct2/show/NCT03781284.

Indexed as

Colitis, UlcerativeFluorodeoxyglucose F18Diffusion Magnetic Resonance ImagingHumansInflammationMagnetic Resonance ImagingFluorodeoxyglucose F18Inflammatory bowel diseasesPETPET/MRUlcerative colitis

Identifiers

PMID31650217
OpenAlexW2981370423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.