Evidence map›Paper›PMID 31650188›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2020

Grip strength in men and women aged 50-79 years is associated with non-vertebral osteoporotic fracture during 15 years follow-up: The Tromsø Study 1994-1995.

A J Søgaard, J H Magnus, Å Bjørnerem, K Holvik, A H Ranhoff, N Emaus, H E Meyer, B H Strand

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Physical capability, physical activity, and their association with femoral bone mineral density in adults aged 40 years and older: The Tromsø study 2015-2016.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  8. Study on Omentin-1 and miR-502-3p in osteoporotic fracture.Journal of musculoskeletal & neuronal interactions · 2021
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

A J SøgaardDivision of Mental and Physical Health, Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, PO Box 222 Skøyen, N-0213, Oslo, Norway. anne.johanne.sogaard@fhi.no.ORCID http://orcid.org/0000-0001-8352-4261
J H MagnusFaculty of Medicine, University of Oslo, Oslo, Norway.
Å BjørneremDepartment of Clinical Medicine, UiT The Arctic University of Norway, Tromsø, Norway.
K HolvikDivision of Mental and Physical Health, Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, PO Box 222 Skøyen, N-0213, Oslo, Norway.
A H RanhoffDivision of Mental and Physical Health, Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, PO Box 222 Skøyen, N-0213, Oslo, Norway.
N EmausDepartment of Health and Care Sciences, UiT The Arctic University of Norway, Tromsø, Norway.
H E MeyerDivision of Mental and Physical Health, Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, PO Box 222 Skøyen, N-0213, Oslo, Norway.
B H StrandDivision of Mental and Physical Health, Department of Chronic Diseases and Ageing, Norwegian Institute of Public Health, PO Box 222 Skøyen, N-0213, Oslo, Norway.
Norwegian Institute of Public Health · NOUiT The Arctic University of Norway · NOUniversity Hospital of North Norway · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In 50-79-year-olds who participated in the Tromsø Study (1994-1995), the risk of non-vertebral osteoporotic fractures during 15 years follow-up increased by 22% in men and 9% in women per 1 SD lower grip strength. The strongest association was observed in men aged 50-64 years.

introductionWe aimed to explore whether low grip strength was associated with increased risk of non-vertebral osteoporotic fracture in the population-based Tromsø Study 1994-1995.

methodsGrip strength (bar) was measured by a Martin Vigorimeter and fractures were retrieved from the X-ray archives at the University Hospital of North Norway between 1994 and 2010. At baseline, weight and height were measured, whereas information on the other covariates were obtained through self-reported questionnaires. Cox regression was used to estimate the hazard ratio (HR) of fracture in age- and gender-specific quintiles of grip-strength, and per 1 SD lower grip strength. Similar analyses were done solely for hip fractures. Adjustments were made for age, height, body mass index (BMI), marital status, education, smoking, physical activity, use of alcohol, self-perceived health, and self-reported diseases.

resultsIn 2891 men and 4002 women aged 50-79 years, 1099 non-vertebral osteoporotic fractures-including 393 hip fractures-were sustained during the median 15 years follow-up. Risk of non-vertebral osteoporotic fracture increased with declining grip strength: hazard ratios per SD decline was 1.22 (95% CI 1.05-1.43) in men and 1.09 (95% CI 1.01-1.18) in women. HR for fracture in lower vs. upper quintile was 1.58 (95% CI 1.02-2.45) in men and 1.28 (95% CI 1.03-1.59) in women. The association was most pronounced in men aged 50-64 years with HR = 3.39 (95% CI 1.76-6.53) in the lower compared to the upper quintile.

conclusionsThe risk of non-vertebral osteoporotic fracture increased with declining grip-strength in both genders, particularly in men aged 50-64 years.

Indexed as

Hand StrengthHip FracturesOsteoporotic FracturesSpinal FracturesAgedBone DensityFemaleHumansMaleMiddle AgedNorwayRisk FactorsAgeCohort studyGenderGrip strengthHip fractureNon-vertebral osteoporotic fracture

Identifiers

PMID31650188
OpenAlexW2982267947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.