Evidence map›Paper›PMID 31650045›Full record

ArticleClinical and translational radiation oncology2019

Fractional exhaled nitric oxide as a potential biomarker for radiation pneumonitis in patients with non-small cell lung cancer: A pilot study.

W M Szejniuk, M S Nielsen, D Brønnum, Z Takács-Szabó, U M Weinreich, L Pilegaard Thomsen, M Bøgsted, I Jensen, T McCulloch, U G Falkmer and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Comparing the utility of lung function parameters and fractional exhaled nitric oxide in predicting lung cancer.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
  4. Review
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

W M SzejniukDept. of Oncology, Aalborg University Hospital, Denmark.
M S NielsenDept. of Medical Physics, Aalborg University Hospital, Denmark.
D BrønnumCentre for Clinical Research, North Denmark Regional Hospital, Hjørring, Denmark.
Z Takács-SzabóDept. of Radiology, Aalborg University Hospital, Denmark.
U M WeinreichDept. of Respiratory Diseases, Aalborg University Hospital, Denmark.
L Pilegaard ThomsenDept. of Health Science and Technology, Aalborg University, Denmark.
M BøgstedClinical Cancer Research Center, Aalborg University Hospital, Denmark.
I JensenDept. of Medical Physics, Aalborg University Hospital, Denmark.
T McCullochDept. of Oncology, Aalborg University Hospital, Denmark.
U G FalkmerDept. of Oncology, Aalborg University Hospital, Denmark.
J CarlDept. of Oncology, Naestved Hospital, Zealand University Hospital, Denmark.
O D RøeDept. of Oncology, Aalborg University Hospital, Denmark.
Aalborg University Hospital · DKAalborg University · DKNorth Denmark Region · DKZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of the study was to investigate repetitive fractional exhaled nitric oxide (FeNO) measurements during high-dose radiation therapy (HDRT) and to evaluate the use of FeNO to predict symptomatic radiation pneumonitis (RP) in patients being treated for non-small cell lung cancer (NSCLC). MATERIALS AND

methodsA total of 50 patients with NSCLC referred for HDRT were enrolled. FeNO was measured at baseline, weekly during HDRT, one month- and every third month after HDRT for a one-year follow-up period. The mean FeNO

resultsA total of 42 patients completed HDRT and weekly FeNO measurements. Grade ≥ 2 of RP was diagnosed in 24 (57%) patients. The mean FeNO

conclusionsThe mean FeNO

Indexed as

Fractional exhaled nitric oxideNon-small cell lung cancerRadiation pneumonitisThoracic radiation therapy

Identifiers

PMID31650045
PMCPMC6804548
OpenAlexW2977057426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.