Evidence map›Paper›PMID 31649887›Full record

ArticleFrontiers in oncology2019

Circulating Tumor Biomarkers in Meningiomas Reveal a Signature of Equilibrium Between Tumor Growth and Immune Modulation.

Erdogan Pekcan Erkan, Thomas Ströbel, Christian Dorfer, Markus Sonntagbauer, Andreas Weinhäusel, Nurten Saydam, Okay Saydam

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. TheInternational journal of molecular sciences · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Meningiomas of the Planum Sphenoidale and Tuberculum Sella.Journal of neurological surgery. Part B, Skull base · 2021
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Erdogan Pekcan ErkanResearch Program in Systems Oncology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Thomas StröbelInstitute of Neurology, Medical University of Vienna, Vienna, Austria.
Christian DorferDepartment of Neurosurgery, Medical University of Vienna, Vienna, Austria.
Markus SonntagbauerAustrian Institute of Technology, Molecular Diagnostics Center for Health and Bioresources, Vienna, Austria.
Andreas WeinhäuselAustrian Institute of Technology, Molecular Diagnostics Center for Health and Bioresources, Vienna, Austria.
Nurten SaydamDepartment of Biochemistry, Molecular Biology, and Biophysics, Medical School, University of Minnesota, Minneapolis, MN, United States.
Okay SaydamDivision of Hematology and Oncology, Department of Pediatrics, Medical School, University of Minnesota, Minneapolis, MN, United States.
Austrian Institute of Technology · ATMedical University of Vienna · ATUniversity of Minnesota Medical Center · USUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meningiomas are primary central nervous system (CNS) tumors that originate from the arachnoid cells of the meninges. Recurrence occurs in higher grade meningiomas and a small subset of Grade I meningiomas with benign histology. Currently, there are no established circulating tumor markers which can be used for diagnostic and prognostic purposes in a non-invasive way for meningiomas. Here, we aimed to identify potential biomarkers of meningioma in patient sera. For this purpose, we collected preoperative (

Indexed as

biomarkerCNS tumorshigh-throughput immunoassay cancer panelmeningiomaproximity extension assayserum biomarker

Identifiers

PMID31649887
PMCPMC6795693
OpenAlexW2980252037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.