Evidence map›Paper›PMID 31649786›Full record

ReviewPrzeglad gastroenterologiczny2019

Therapeutic applicability of helminths in autoimmune diseases - literature overview.

Jacek Zwiernik, Tomasz Arłukowicz, Beata Zwiernik, Tomasz Matyskieła, Marta Gimeła-Dargiewicz, Agnieszka Rakowska, Beata Januszko-Giergielewicz, Ewa Rotkiewicz

Open access · goldAbstract readReview
In one paragraph

Review in Przeglad gastroenterologiczny, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jacek ZwiernikDepartment of Neurology, University of Warmia and Mazury, Olsztyn, Poland.
Tomasz ArłukowiczDepartment of Internal Medicine, University of Warmia and Mazury, Olsztyn, Poland.
Beata ZwiernikDepartment of Neurology, University of Warmia and Mazury, Olsztyn, Poland.
Tomasz MatyskiełaDepartment of Neurology, University of Warmia and Mazury, Olsztyn, Poland.
Marta Gimeła-DargiewiczClinic of Neurology, University of Warmia and Mazury, Olsztyn, Poland.
Agnieszka RakowskaClinic of Neurology, University of Warmia and Mazury, Olsztyn, Poland.
Beata Januszko-GiergielewiczDepartment of Transplantology and General Surgery, Provincial Specialist Hospital, Olsztyn, Poland.
Ewa RotkiewiczNeurology Ward, Provincial Specialist Hospital, Olsztyn, Poland.
University of Warmia and Mazury in Olsztyn · PLUniversity of Computer Sciences and Economics in Olsztyn · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper presents an overview of published studies conducted on helminths - parasites of the human gastrointestinal tract. Making use of their ability for immunomodulation may lead to the introduction of effective therapies for autoimmune diseases. This paper presents chronologically attempts to treat autoimmune diseases not only of the gastrointestinal tract, but also of the nervous and endocrine systems, which have been undertaken for decades. The overview of analysed reports demonstrates that as medical knowledge on the cells and mediators participating actively in inflammatory processes accumulates, clinical trials focus on ever more specific areas concerning the pathomechanisms of autoimmune diseases. The outcomes of clinical trials conducted both on animals and humans give reasons to assume that the modification of the human intestinal microflora may be the key to fighting against these diseases.

Indexed as

autoimmune diseaseshelminthsmicrobiota

Identifiers

PMID31649786
PMCPMC6807663
OpenAlexW2979844465

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.