Evidence map›Paper›PMID 31649733›Full record

ArticleFrontiers in genetics2019

CEPICS: A Comparison and Evaluation Platform for Integration Methods in Cancer Subtyping.

Ran Duan, Lin Gao, Han Xu, Kuo Song, Yuxuan Hu, Hongda Wang, Yongqiang Dong, Chenxing Zhang, Songwei Jia

Abstract read
In one paragraph

Article in Frontiers in genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Multi-omics peripheral and core regions of cancer.NPJ systems biology and applications · 2022
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ran DuanSchool of Computer Science and Technology, Xidian University, Xi'an, China.
Lin GaoSchool of Computer Science and Technology, Xidian University, Xi'an, China.
Han XuSchool of Computer Science and Technology, Xidian University, Xi'an, China.
Kuo SongSchool of Computer Science and Technology, Xidian University, Xi'an, China.
Yuxuan HuSchool of Computer Science and Technology, Xidian University, Xi'an, China.
Hongda WangSchool of Computer Science and Technology, Xidian University, Xi'an, China.
Yongqiang DongSchool of Computer Science and Technology, Xidian University, Xi'an, China.
Chenxing ZhangSchool of Computer Science and Technology, Xidian University, Xi'an, China.
Songwei JiaSchool of Computer Science and Technology, Xidian University, Xi'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer subtypes can improve our understanding of cancer, and suggest more precise treatment for patients. Multi-omics molecular data can characterize cancers at different levels. Up to now, many computational methods that integrate multi-omics data for cancer subtyping have been proposed. However, there are no consistent criteria to evaluate the integration methods due to the lack of gold standards (e.g., the number of subtypes in a specific cancer). Since comprehensive evaluation and comparison between different methods serves as a useful tool or guideline for users to select an optimal method for their own purpose, we develop a scalable platform, CEPICS, for comprehensively evaluating and comparing multi-omics data integration methods in cancer subtyping. Given a user-specified maximum number of subtypes,

Indexed as

cancer subtypescluster analysisdata integrationmulti-omicsR package

Identifiers

PMID31649733
PMCPMC6792302

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.